{"id":"W2052617539","doi":"10.1126/science.1220967","title":"Whole-Genome Sequencing: The New Standard of Care?","year":2012,"lang":"en","type":"article","venue":"Science","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"","keywords":"Genome; Computational biology; Whole genome sequencing; Biology; Evolutionary biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.08210124,0.001619526,0.004427411,0.002644582,0.001294542,0.008186536,0.004979433,0.009904828,0.01158415],"category_scores_gemma":[0.08745896,0.0009449283,0.001444408,0.003370681,0.01108798,0.01701157,0.005111529,0.01680855,0.007456521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003242401,"about_ca_system_score_gemma":0.006719096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004633266,"about_ca_topic_score_gemma":0.004932662,"domain_scores_codex":[0.973167,0.01308043,0.001487054,0.003716493,0.007617204,0.0009317847],"domain_scores_gemma":[0.8950016,0.05747905,0.005260363,0.0160761,0.01778619,0.00839675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001651401,0.0001632522,0.01204607,0.003163573,0.0007092591,0.0004255776,0.000750019,0.001582367,0.007159561,0.09269562,0.3478158,0.5318374],"study_design_scores_gemma":[0.0002891693,0.0005594988,0.008786658,0.003540096,0.0004066365,0.001645924,0.001384221,0.003675524,0.002708929,0.3047816,0.6718913,0.0003305443],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002854326,0.1311038,0.1084391,0.7338974,0.01376048,0.00009964881,0.001132925,0.001436083,0.007276262],"genre_scores_gemma":[0.0842804,0.2472315,0.1839749,0.4261717,0.04222747,0.0006115949,0.002947307,0.001302496,0.01125265],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.08210124,"threshold_uncertainty_score":0.434198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01125850180934129,"score_gpt":0.2553596148538899,"score_spread":0.2441011130445486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}