{"id":"W2052619363","doi":"10.1073/pnas.1402383111","title":"Cellular heterogeneity profiling by hyaluronan probes reveals an invasive but slow-growing breast tumor subset","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Alberta; London Health Sciences Centre","funders":"National Cancer Institute","keywords":"CD44; Biology; Flow cytometry; Cancer research; Cell culture; In vivo; Phenotype; Receptor; Motility; Tumor progression; Metastasis; Molecular biology; Cell; Cancer; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001764539,0.0001395865,0.000167491,0.00008297941,0.0002534667,0.00004132007,0.00104606,0.0001047497,0.000003759146],"category_scores_gemma":[0.000509819,0.00009977018,0.00008796201,0.0003032885,0.0006901255,0.00006693148,0.0002580456,0.0001516647,7.707974e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001805393,"about_ca_system_score_gemma":0.00007263813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001914694,"about_ca_topic_score_gemma":4.019642e-7,"domain_scores_codex":[0.9980386,0.00003120486,0.0003112454,0.0004395808,0.000898117,0.0002811898],"domain_scores_gemma":[0.9992223,0.00002950861,0.0002850641,0.00002521038,0.0003530674,0.00008487297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002913246,0.00005054308,0.01362485,0.00007935393,0.00001346367,9.127723e-9,0.00001609108,0.00003030147,0.9843338,0.001269166,0.0002210501,0.0003323031],"study_design_scores_gemma":[0.0001801916,0.0002432269,0.006787836,0.00005323249,0.000006743697,0.00001849202,0.00008024017,0.0004286062,0.9896452,0.002251102,0.0001821182,0.0001230263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982591,0.0001626284,0.00001105182,0.0005348287,0.00001173125,0.0003070357,0.00009737435,0.000006063238,0.0006101883],"genre_scores_gemma":[0.9981334,0.00001299641,0.001291645,0.0002682791,0.0001354614,0.00003172603,0.000005037914,0.000008974261,0.0001125265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006837014,"threshold_uncertainty_score":0.406851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02582202203169085,"score_gpt":0.2915824789674948,"score_spread":0.2657604569358039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}