{"id":"W2052691998","doi":"10.1016/j.devcel.2012.08.002","title":"Lipid Sorting by Ceramide Structure from Plasma Membrane to ER for the Cholera Toxin Receptor Ganglioside GM1","year":2012,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Center for Research Resources; National Institute of General Medical Sciences; National Institutes of Natural Sciences; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Harvard Digestive Diseases Center, Harvard University","keywords":"Cholera toxin; Glycosphingolipid; Ceramide; Endoplasmic reticulum; Ganglioside; Biology; Cell biology; Lipid raft; Golgi apparatus; Endosome; Biochemistry; Cell membrane; Receptor; Cell; Signal transduction; Microbiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001433077,0.0001368017,0.0001456263,0.0002193975,0.0004704249,0.0005420893,0.0002266614,0.0002800539,0.001229199],"category_scores_gemma":[0.000265071,0.0001343955,0.000142989,0.0001507174,0.0002359013,0.0004142448,0.0003020205,0.0005162337,0.0006424151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001500492,"about_ca_system_score_gemma":0.0005786392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002529438,"about_ca_topic_score_gemma":0.0028243,"domain_scores_codex":[0.9999337,0.000008929818,0.000004336423,0.0000120068,0.00001803847,0.00002307013],"domain_scores_gemma":[0.9999312,0.000012171,0.00001166671,0.000007549282,0.00002192076,0.00001549361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001718928,0.0000045778,0.0002412706,0.0000181295,0.0000015663,0.00006023207,0.00003039811,0.0001848422,0.9973604,0.0008333809,0.00005470016,0.00103863],"study_design_scores_gemma":[0.00001369816,0.00003172763,0.002589067,0.000006989284,0.000006616198,0.0002030047,0.0001110385,0.002743602,0.9922535,0.0003628231,0.001667813,0.0000101193],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961247,0.0005552925,0.001551807,0.0002525107,0.00001768894,0.000006544801,0.0001158406,0.00002107528,0.001354577],"genre_scores_gemma":[0.9940654,0.0006771156,0.001523587,0.00007556336,0.000004017246,0.000005460944,0.0003311324,0.00003387359,0.003283774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002529438,"threshold_uncertainty_score":0.01088685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008680066148478561,"score_gpt":0.2259142803674772,"score_spread":0.2172342142189986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}