{"id":"W2052707876","doi":"10.1158/0008-5472.sabcs13-p1-08-09","title":"Abstract P1-08-09: EGFR expression is associated with decreased response from HER2 targeted therapeutics in the neo-adjuvant setting in the NeoALTTO trial","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Smiths Detection (Canada)","funders":"","keywords":"Lapatinib; Medicine; Trastuzumab; Oncology; Internal medicine; Breast cancer; Adjuvant; Cancer; Pathological; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001153252,0.0004272038,0.000792745,0.0001246648,0.0001302952,0.0006093802,0.0002453192,0.0005535355,0.002623087],"category_scores_gemma":[0.0008660863,0.0001210844,0.0005574774,0.0001224242,0.0004095935,0.0004898114,0.0002778916,0.001211264,0.0003505778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003088591,"about_ca_system_score_gemma":0.0002986834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000135376,"about_ca_topic_score_gemma":0.0005707091,"domain_scores_codex":[0.999676,0.0001666561,0.00002320572,0.00005765674,0.00004662422,0.00002983548],"domain_scores_gemma":[0.999286,0.0002058252,0.0001955193,0.00006523434,0.00004578887,0.0002017574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8414803,0.004640722,0.03742765,0.0006915457,0.001611247,0.0002373872,0.0001294277,0.00180367,0.05320609,0.0005294014,0.007131671,0.05111083],"study_design_scores_gemma":[0.4157046,0.2430366,0.2884014,0.0001892621,0.003494561,0.001634087,0.0001650529,0.006864439,0.02033056,0.002181455,0.01788008,0.0001178219],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937764,0.0009664034,0.0002342225,0.0006726003,0.00007244501,0.0002389098,0.0007346024,0.00003329886,0.003270967],"genre_scores_gemma":[0.9943919,0.0002894186,0.0003726862,0.0008696118,0.0001056608,0.0002575323,0.001515734,0.00001663911,0.002180883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002623087,"threshold_uncertainty_score":0.008775055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1345768610784584,"score_gpt":0.4477739577996906,"score_spread":0.3131970967212322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}