{"id":"W2052710970","doi":"10.1038/leu.2012.100","title":"Consensus guidelines for the conduct and reporting of clinical trials in systemic light-chain amyloidosis","year":2012,"lang":"en","type":"review","venue":"Leukemia","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":383,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute; Amyloidosis Foundation","keywords":"Clinical trial; AL amyloidosis; Amyloidosis; Medicine; Drug development; Clinical research; Consensus conference; Intensive care medicine; Medical physics; Pathology; Immunoglobulin light chain; Immunology; Drug; Internal medicine; Pharmacology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.1651842,0.003695736,0.01564894,0.009662689,0.002570125,0.01107642,0.01722086,0.01687944,0.009703553],"category_scores_gemma":[0.223946,0.003032938,0.02074675,0.009476806,0.005128975,0.005327334,0.005664929,0.01371779,0.006814987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.007410902,"about_ca_system_score_gemma":0.03376731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006411347,"about_ca_topic_score_gemma":0.007274535,"domain_scores_codex":[0.8207181,0.09903757,0.05707451,0.003931109,0.01661473,0.00262399],"domain_scores_gemma":[0.6737946,0.1962021,0.05023643,0.01222507,0.06241859,0.005123358],"domain_codex":null,"domain_gemma":"reporting","domain_candidate":"reporting","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003049725,0.0002813241,0.000855358,0.1754588,0.00585033,0.0005783431,0.0007583163,0.001736182,0.001417592,0.01421726,0.2209454,0.5748512],"study_design_scores_gemma":[0.00519378,0.0005910379,0.003709511,0.2870322,0.01389376,0.00106362,0.0004353151,0.001176317,0.001539363,0.02373319,0.6613806,0.0002512783],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"methods","genre_scores_codex":[0.0009048447,0.8353828,0.04513973,0.05992204,0.01441447,0.02110636,0.007448123,0.00116092,0.01452075],"genre_scores_gemma":[0.0122759,0.6041397,0.2574359,0.03602054,0.007332033,0.0636225,0.009812214,0.0005783702,0.008782843],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.8348157,"threshold_uncertainty_score":0.8735882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5067914328514087,"score_gpt":0.5326453283260147,"score_spread":0.02585389547460604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}