{"id":"W2052827297","doi":"10.1074/jbc.m405712200","title":"Domain Swapping Localizes the Structural Determinants of Regioselectivity in Membrane-bound Fatty Acid Desaturases of Caenorhabditis elegans","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":true,"has_abstract":true,"ca_institutions":"Plant Biotechnology Institute","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Regioselectivity; Caenorhabditis elegans; Biochemistry; Chemistry; Stereochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":{"nature":"Retraction","reason":"Misconduct by Author;","date":"6/23/2006 0:00","openalex_flagged":true},"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001314273,0.000261208,0.0001981623,0.0002361369,0.0001421156,0.0002257626,0.0002926214,0.0002748186,0.0005877889],"category_scores_gemma":[0.0001939439,0.0002008766,0.0003236611,0.0001588837,0.0003053326,0.0001113284,0.0002665877,0.0005706509,0.0002337736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005698042,"about_ca_system_score_gemma":0.0003175875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001990667,"about_ca_topic_score_gemma":0.003259136,"domain_scores_codex":[0.9998779,0.00001110883,0.000016338,0.00003734354,0.00003027175,0.00002700346],"domain_scores_gemma":[0.9997538,0.00005572411,0.00008196095,0.00003271743,0.00001955011,0.00005618398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005522149,0.00000940339,0.0001342809,0.000007410987,0.000001998597,0.00002582491,0.000009709051,0.00007638997,0.999222,0.00005552381,0.000005040305,0.0003970553],"study_design_scores_gemma":[0.00001628449,0.0001033666,0.006787105,0.000006107794,0.00001318611,0.0001553936,0.00004027786,0.001618641,0.9903749,0.0000464154,0.0008266123,0.00001172222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983922,0.0001030776,0.0009354437,0.00001751411,0.000007044862,0.00001280606,0.0001538373,0.00002021752,0.0003578395],"genre_scores_gemma":[0.9966653,0.0001200336,0.002045102,0.00002755724,0.00000174483,0.00001847426,0.0003050618,0.00002846374,0.0007882319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001990667,"threshold_uncertainty_score":0.004134238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01406042489186666,"score_gpt":0.2469723462700065,"score_spread":0.2329119213781398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}