{"id":"W2052867812","doi":"10.1016/j.cjca.2012.03.003","title":"Utility of Biomarkers and Imaging in the Development of Drugs for the Treatment of Coronary Atherosclerosis","year":2012,"lang":"en","type":"review","venue":"Canadian Journal of Cardiology","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Medicine; Ezetimibe; Clinical trial; Rimonabant; Niacin; Drug development; Internal medicine; Cholesterylester transfer protein; Cholesterol; Cardiology; Lipoprotein; Drug; Pharmacology; Cannabinoid receptor; Receptor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002085606,0.001489405,0.004061281,0.003956211,0.0003777809,0.001680917,0.001356273,0.002247655,0.002363079],"category_scores_gemma":[0.002537908,0.0005482163,0.001067904,0.003042661,0.001067074,0.001518997,0.0007943988,0.003561962,0.001390804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001120963,"about_ca_system_score_gemma":0.00225826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00362767,"about_ca_topic_score_gemma":0.006529524,"domain_scores_codex":[0.9994141,0.0001193313,0.00008656848,0.00007968493,0.0002610059,0.00003921947],"domain_scores_gemma":[0.9977632,0.001358476,0.0002387952,0.00004413634,0.0005085779,0.00008674967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001486751,0.0001482171,0.0004454158,0.01426621,0.0002746789,0.0003175703,0.00004134161,0.00044785,0.001559654,0.003978726,0.013965,0.9644068],"study_design_scores_gemma":[0.0001427431,0.0003513398,0.003365156,0.01083426,0.0009096554,0.003071824,0.0001238402,0.0005240238,0.00181687,0.005208003,0.9735444,0.0001080303],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005990435,0.9991933,0.0001377958,0.0002308744,0.00007764406,0.00000351822,0.000009042116,0.000003327881,0.0002846713],"genre_scores_gemma":[0.0005452817,0.9985923,0.0003531603,0.0001937389,0.0001475802,0.000004774117,0.00001532694,8.921944e-7,0.0001469186],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004061281,"threshold_uncertainty_score":0.0110299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07800721323232034,"score_gpt":0.3161472918992581,"score_spread":0.2381400786669378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}