{"id":"W2052873409","doi":"10.1371/journal.pone.0112093","title":"Alkaloids Modulate Motility, Biofilm Formation and Antibiotic Susceptibility of Uropathogenic Escherichia coli","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Piperaceae Chemical and Biological Studies","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biofilm; Escherichia coli; Swarming motility; Microbiology; Piperine; Antibiotics; Motility; Bacteria; Bacterial adhesin; Biology; Ciprofloxacin; Virulence; Chemistry; Gene; Quorum sensing; Biochemistry; Pharmacology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009353909,0.0001824402,0.0001580907,0.0001475585,0.00009371176,0.0001701903,0.00009755489,0.0002537443,0.000913337],"category_scores_gemma":[0.0001693361,0.00009555942,0.0001392934,0.0000905703,0.00009948553,0.0001379053,0.0001237274,0.0002517545,0.0001146576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009776126,"about_ca_system_score_gemma":0.0001212778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003977743,"about_ca_topic_score_gemma":0.00088917,"domain_scores_codex":[0.9999365,0.00002151767,0.000006386432,0.000007753005,0.00001486918,0.00001292516],"domain_scores_gemma":[0.9999087,0.00002635351,0.00002821727,0.000006430618,0.00001481926,0.00001543774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001690022,0.00005794737,0.000243586,0.00005348492,0.000003833257,0.00002475229,0.00001527172,0.00003706828,0.9981197,0.00001341534,0.00001682901,0.001245257],"study_design_scores_gemma":[0.00003895853,0.00231198,0.0344056,0.00002502181,0.00003752835,0.0001802794,0.0001075351,0.00101222,0.9603126,0.00004998835,0.001508941,0.000009454796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974338,0.001470125,0.0002185838,0.00006153737,0.000007496178,0.00001532168,0.00009134949,0.00001328891,0.0006884048],"genre_scores_gemma":[0.996854,0.001179062,0.000770962,0.00004315877,0.000004613279,0.00001705925,0.0001210018,0.000003181228,0.001007046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000913337,"threshold_uncertainty_score":0.003055453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.138275161553409,"score_gpt":0.3382402950740736,"score_spread":0.1999651335206646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}