{"id":"W2052904519","doi":"10.1039/c0an00741b","title":"Towards an early diagnosis of HIV infection: an electrochemical approach for detection ofHIV-1 reverse transcriptase enzyme","year":2010,"lang":"en","type":"article","venue":"The Analyst","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada","keywords":"Detection limit; Chemistry; Self-assembled monolayer; Cystamine; Peptide; Reverse transcriptase; Dielectric spectroscopy; Electrochemistry; Biosensor; Enzyme; Combinatorial chemistry; Cyclic voltammetry; Ferrocene; Redox; Linear range; Monolayer; Electrode; Chromatography; Biochemistry; Inorganic chemistry; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008184583,0.0009081846,0.0005966213,0.0006758332,0.0001618966,0.0007301839,0.0008048866,0.001508005,0.0007016192],"category_scores_gemma":[0.0007605913,0.0003924179,0.0003062369,0.0002700638,0.0003472774,0.0006270599,0.0004306809,0.001425582,0.0005870045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003251806,"about_ca_system_score_gemma":0.000201773,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001666746,"about_ca_topic_score_gemma":0.0004750908,"domain_scores_codex":[0.9993293,0.0001745769,0.00003710195,0.0001547797,0.0002593976,0.00004499881],"domain_scores_gemma":[0.999685,0.0001416954,0.0000391159,0.00001936376,0.00008495745,0.00002980859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004048615,0.0000280686,0.0002290793,0.0001882464,0.00001017279,0.00003374592,0.00001500355,0.00006178158,0.9881139,0.0001860839,0.00008524931,0.01100818],"study_design_scores_gemma":[0.00001490394,0.0002369595,0.0009714059,0.00002089592,0.0000323527,0.000658755,0.00002347891,0.003563202,0.9905829,0.0002886732,0.003589854,0.00001660265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.3387231,0.08897372,0.562088,0.002618259,0.001172277,0.0004306664,0.0008254698,0.001275695,0.003892899],"genre_scores_gemma":[0.543064,0.0334169,0.415237,0.001313836,0.0003707443,0.0002148693,0.000515602,0.00003902682,0.005827945],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.001508005,"threshold_uncertainty_score":0.004328489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0110054093975457,"score_gpt":0.2674807415241918,"score_spread":0.2564753321266461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}