{"id":"W2052939347","doi":"10.1371/journal.pone.0024156","title":"Critical Period of Nonpromoter DNA Methylation Acquisition during Prenatal Male Germ Cell Development","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Montreal Children's Hospital","funders":"Canadian Institutes of Health Research; McGill University Health Centre; Institute of Genetics; McGill University","keywords":"DNA methylation; Biology; Epigenetics; Methylation; Germ cell; Genetics; Germline; Somatic cell; RNA-Directed DNA Methylation; Andrology; Molecular biology; DNA; Gene; Gene expression; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011219,0.0001703374,0.000258669,0.0003237203,0.0001794101,0.0002898078,0.0001765077,0.0002454308,0.001592119],"category_scores_gemma":[0.0002362047,0.0002028867,0.0001311861,0.0001153988,0.0002237203,0.0002973534,0.0003824093,0.0005019901,0.0003879004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002859416,"about_ca_system_score_gemma":0.0002944666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008705445,"about_ca_topic_score_gemma":0.001319033,"domain_scores_codex":[0.9998708,0.00001121689,0.00001025352,0.00004345669,0.00003416428,0.00003005571],"domain_scores_gemma":[0.9997459,0.00003769295,0.00009664728,0.00001750186,0.00003049884,0.00007170827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001007997,0.000008419127,0.003853337,0.00003221225,0.000003417626,0.0001104305,0.00006452408,0.00002524376,0.9934999,0.0001136822,0.00002346533,0.002164555],"study_design_scores_gemma":[0.000006466355,0.000299476,0.2634449,0.00002569149,0.00001489083,0.0008104952,0.0001212387,0.0002039277,0.7315183,0.000148313,0.003395954,0.00001034589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918873,0.002739056,0.003318281,0.00003983033,0.00001398349,0.00002264599,0.0005217246,0.00009203056,0.001365224],"genre_scores_gemma":[0.9940572,0.001251167,0.00201025,0.00004874167,0.000009394284,0.00003226691,0.0007017155,0.00002016909,0.001869066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001592119,"threshold_uncertainty_score":0.005326211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02927735762690146,"score_gpt":0.2290504731353989,"score_spread":0.1997731155084974,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}