{"id":"W2052956178","doi":"10.1371/journal.pntd.0001923","title":"Cathepsin B & L Are Not Required for Ebola Virus Replication","year":2012,"lang":"en","type":"article","venue":"PLoS neglected tropical diseases","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"Public Health Agency of Canada; National Institutes of Health; Public Health Agency; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Division of Intramural Research, National Institute of Allergy and Infectious Diseases","keywords":"Ebola virus; Virology; Cathepsin L; Viral replication; Replication (statistics); Ebolavirus; Biology; Neglected tropical diseases; Cathepsin S; Cathepsin B; Virus; Medicine; Cathepsin; Enzyme; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001995255,0.0002353924,0.00042122,0.0002558756,0.0002681607,0.0007233515,0.0003760721,0.0004417978,0.001687124],"category_scores_gemma":[0.0005962547,0.0002132821,0.0003375461,0.0001650519,0.0003463579,0.0003884414,0.0003014297,0.0005341233,0.0006130405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000481436,"about_ca_system_score_gemma":0.0004150613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001218855,"about_ca_topic_score_gemma":0.001692401,"domain_scores_codex":[0.9996312,0.00007946862,0.00005696682,0.00007024796,0.00008463151,0.00007750687],"domain_scores_gemma":[0.9994861,0.0001162903,0.0001311173,0.0000894331,0.00006153181,0.000115578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001971774,0.00004339202,0.0006876965,0.00006469025,0.000009361809,0.0001505872,0.00002185028,0.00004124924,0.9977203,0.0001223618,0.00007652091,0.00086469],"study_design_scores_gemma":[0.0000583045,0.0003516047,0.02390744,0.00002945745,0.0000261881,0.001746436,0.0001288576,0.001022265,0.9596732,0.0001314555,0.01290729,0.00001742681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888961,0.005986588,0.001808027,0.000259692,0.00007114604,0.00004720744,0.00112867,0.00007269997,0.001729815],"genre_scores_gemma":[0.9919814,0.001012434,0.001770172,0.00009600492,0.00001202485,0.00007493339,0.001731643,0.00002580935,0.00329552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001687124,"threshold_uncertainty_score":0.005643964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0867431222380759,"score_gpt":0.3565302521151761,"score_spread":0.2697871298771002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}