{"id":"W2052956178","doi":"10.1371/journal.pntd.0001923","title":"Cathepsin B & L Are Not Required for Ebola Virus Replication","year":2012,"lang":"en","type":"article","venue":"PLoS neglected tropical diseases","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"Public Health Agency of Canada; National Institutes of Health; Public Health Agency; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Division of Intramural Research, National Institute of Allergy and Infectious Diseases","keywords":"Ebola virus; Virology; Cathepsin L; Viral replication; Replication (statistics); Ebolavirus; Biology; Neglected tropical diseases; Cathepsin S; Cathepsin B; Virus; Medicine; Cathepsin; Enzyme; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000007766097,0.0001585215,0.0002869459,0.0001324666,0.0001948222,0.00003667574,0.00008182794,0.000108796,0.000301184],"category_scores_gemma":[0.00173614,0.0001279297,0.0001929408,0.0003259863,0.00008907489,0.0001562748,0.00004080138,0.0001612695,0.0002246458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001296238,"about_ca_system_score_gemma":0.00008061202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004487765,"about_ca_topic_score_gemma":0.0000194107,"domain_scores_codex":[0.9985214,0.00007377354,0.0002534874,0.0003413445,0.0003097179,0.0005002177],"domain_scores_gemma":[0.9983896,0.0001748957,0.00007071179,0.0005661925,0.0002670787,0.0005315022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0013323,0.002971363,0.04978936,0.0002333064,0.0001649309,0.000003728765,0.00005777324,7.180182e-7,0.9300693,0.0008030083,0.009560402,0.005013851],"study_design_scores_gemma":[0.001151144,0.000241141,0.9393625,0.00007941538,0.0002991185,0.00001151468,0.00001332068,0.0002148649,0.03785776,0.0001313333,0.02048165,0.0001561889],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993608,0.0006768802,0.00194889,0.001779121,0.00009825335,0.001000548,0.0002362503,0.0002882386,0.0003638088],"genre_scores_gemma":[0.9959762,0.00007822762,0.0006268651,0.0006344435,0.0007730728,0.0004752556,0.0002858519,0.00003991719,0.001110236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8922115,"threshold_uncertainty_score":0.5216823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0867431222380759,"score_gpt":0.3565302521151761,"score_spread":0.2697871298771002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}