{"id":"W2052956903","doi":"10.2147/cmar.s52217","title":"Proactive strategies for regorafenib in metastatic colorectal cancer: implications for optimal patient management","year":2014,"lang":"en","type":"review","venue":"Cancer Management and Research","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bayer HealthCare","keywords":"Regorafenib; Medicine; Colorectal cancer; Bevacizumab; Adverse effect; Oncology; Internal medicine; Irinotecan; Aflibercept; Cancer; Chemotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003567135,0.0004959355,0.001140443,0.0004730526,0.0007561528,0.002203362,0.0009702945,0.001794791,0.002081844],"category_scores_gemma":[0.007077589,0.0001800795,0.0008956647,0.0003656028,0.0007054947,0.002337229,0.001435083,0.005567889,0.0006737158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001355654,"about_ca_system_score_gemma":0.004030546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001394811,"about_ca_topic_score_gemma":0.004154803,"domain_scores_codex":[0.9983407,0.0009048138,0.0002048427,0.0001194071,0.0003085928,0.0001216104],"domain_scores_gemma":[0.9971613,0.001407883,0.0004243254,0.00005659275,0.0005128216,0.0004370708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003248107,0.0003934505,0.003829854,0.006566671,0.0003499904,0.001392741,0.0009892095,0.001866553,0.001444821,0.01557173,0.1370055,0.8302646],"study_design_scores_gemma":[0.0004946576,0.0006597186,0.008362597,0.01766364,0.0004899635,0.003448943,0.00230829,0.001543711,0.0009280608,0.03126399,0.9326911,0.0001452174],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005106245,0.7517766,0.007804337,0.2188213,0.00320436,0.0001750657,0.00009934301,0.0001948684,0.01281786],"genre_scores_gemma":[0.06925626,0.8121556,0.02777781,0.07769213,0.007843033,0.0007125934,0.0002708409,0.00005287796,0.004238907],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003567135,"threshold_uncertainty_score":0.01886499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1807651006745937,"score_gpt":0.494038968045569,"score_spread":0.3132738673709753,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}