{"id":"W2052965857","doi":"10.1006/mgme.2000.2974","title":"A Heteroallelic Mutant Mouse Model: A New Orthologue for Human Hyperphenylalaninemia","year":2000,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Children's Hospital; McGill University","funders":"","keywords":"Hyperphenylalaninemia; Phenylalanine; Phenylalanine hydroxylase; Phenotype; Biology; Mutant; Genetics; Mutagenesis; Tyrosine; Mendelian inheritance; Endocrinology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000411681,0.00122232,0.0007678713,0.002024847,0.0006908554,0.0005360866,0.0009351622,0.001200661,0.004610754],"category_scores_gemma":[0.0003646234,0.0004496597,0.0005277394,0.0004666739,0.0008167548,0.0006830475,0.0006983904,0.001437443,0.0008679801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003070555,"about_ca_system_score_gemma":0.0003857662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005105854,"about_ca_topic_score_gemma":0.0009767333,"domain_scores_codex":[0.9995598,0.00007414324,0.00005991901,0.0001340326,0.0001302481,0.00004186197],"domain_scores_gemma":[0.9995933,0.00008524554,0.0000907184,0.00007360436,0.00002951586,0.0001275852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000516969,0.0001920145,0.0004024867,0.00005960659,0.00003377412,0.002189831,0.00005871511,0.000124701,0.9915252,0.00283302,0.000305491,0.001758182],"study_design_scores_gemma":[0.0005687521,0.001320317,0.01283443,0.00009240684,0.0004726772,0.04175214,0.0002199181,0.005233894,0.911234,0.00363812,0.02254346,0.00008991329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9571432,0.001411909,0.03213862,0.0007469712,0.0002695865,0.0002541066,0.00226233,0.0008375986,0.004935679],"genre_scores_gemma":[0.9662369,0.0016305,0.01869378,0.000304051,0.0001098178,0.0003509308,0.001635089,0.0004081783,0.01063073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004610754,"threshold_uncertainty_score":0.01542449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01004759445377472,"score_gpt":0.2480887405830412,"score_spread":0.2380411461292665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}