{"id":"W2052999954","doi":"10.1158/1538-7445.panca2012-b13","title":"Abstract B13: Whole-genome mutation landscape in pancreatic ductal adenocarcinoma.","year":2012,"lang":"en","type":"article","venue":"Genetics","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Indel; Genome; Somatic cell; Biology; Copy-number variation; Adenocarcinoma; Copy number analysis; Cancer; Pancreatic cancer; Primary tumor; Structural variation; Computational biology; Cancer research; Genetics; Gene; Single-nucleotide polymorphism; Metastasis; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001466598,0.0001564516,0.0001351779,0.00006142019,0.00004016052,0.00002704243,0.0001374677,0.0001540099,0.00004580131],"category_scores_gemma":[0.00005568138,0.0001702887,0.00005648973,0.0000921673,0.00003657236,0.000004276485,0.00007984836,0.00009449184,0.00007366056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000263663,"about_ca_system_score_gemma":0.00006795231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001978026,"about_ca_topic_score_gemma":0.0001052355,"domain_scores_codex":[0.9990186,0.00002100234,0.0002350996,0.0002299685,0.0001091866,0.0003861507],"domain_scores_gemma":[0.9994352,0.00001983322,0.0000707842,0.0003041757,0.00003955044,0.0001303983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004689482,0.0001416715,0.5780675,0.000034398,0.00004112511,0.00001609546,0.0003215046,0.00127526,0.4178367,0.0000503564,0.001134435,0.001034004],"study_design_scores_gemma":[0.0006670711,0.0001618665,0.9661521,0.000008597983,0.00003277662,0.0000471946,0.0002120512,0.00005466044,0.01467047,0.00006941558,0.01762559,0.0002982446],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845008,0.01376336,0.0001786016,0.00006550496,0.0002517811,0.0001665697,0.00008042813,0.000007726217,0.0009852084],"genre_scores_gemma":[0.9968008,0.0007256489,0.0008824476,0.0001770252,0.0007643176,0.00002202426,0.0004910997,0.00003220692,0.000104388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4031663,"threshold_uncertainty_score":0.694417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01018665948567923,"score_gpt":0.235042339532577,"score_spread":0.2248556800468978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}