{"id":"W2053139099","doi":"10.1016/j.neuropharm.2006.06.018","title":"Neuroanatomical and pharmacological assessment of Fos expression induced in the rat brain by the phosphodiesterase-4 inhibitor 6-(4-pyridylmethyl)-8-(3-nitrophenyl) quinoline","year":2006,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University; Merck Canada Inc. (Canada)","funders":"Canadian Institutes of Health Research; Multiple Sclerosis Society; Multiple Sclerosis Society of Canada","keywords":"Phosphodiesterase; Quinoline; Pharmacology; Chemistry; Enzyme; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003511105,0.0002193487,0.0002209242,0.00005184075,0.0001407711,0.00002505657,0.0002594663,0.0001588746,0.00004161684],"category_scores_gemma":[0.00006374345,0.0001323893,0.00007397736,0.0001655318,0.000251295,0.000009934431,0.0001754702,0.0003587077,9.471e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000171617,"about_ca_system_score_gemma":0.00005014905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000241712,"about_ca_topic_score_gemma":0.00001050608,"domain_scores_codex":[0.9978154,0.0008933924,0.0004097645,0.0004131501,0.0001890751,0.0002792612],"domain_scores_gemma":[0.9992352,0.0002805614,0.0001693223,0.0002061679,0.00005722232,0.00005148568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003091425,0.0002638935,0.002238983,0.000009239417,0.00001207923,0.00001658195,0.00002987622,0.00007434495,0.9685658,0.00003305781,0.02762154,0.0008254495],"study_design_scores_gemma":[0.003047793,0.0006606715,0.03380481,0.000005719826,0.00004675056,0.00006475491,0.00005460981,0.0007737799,0.9196777,0.00004211129,0.04163314,0.000188144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944373,0.0006063577,0.00009735736,0.00354337,0.0006225664,0.0005135376,0.00001548505,0.00001339266,0.0001506484],"genre_scores_gemma":[0.9938658,0.0001653763,0.00005154982,0.00534841,0.0002965569,0.00009109691,0.00005912036,0.0000192788,0.0001027458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0488881,"threshold_uncertainty_score":0.5398679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01034602718698597,"score_gpt":0.2919951488165536,"score_spread":0.2816491216295677,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}