{"id":"W2053167145","doi":"10.1042/bj20060043","title":"Evaluation of the membrane-spanning domain of ClC-2","year":2006,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Membrane protein; Proteolysis; Biochemistry; Chloride channel; Biology; Cysteine; Chemistry; Transporter; Membrane; Biophysics; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002237364,0.0003171458,0.0001843842,0.0001607419,0.0002028361,0.0002932319,0.0002206017,0.0003257888,0.0007177807],"category_scores_gemma":[0.0003696835,0.00007789041,0.0001303837,0.0001716116,0.0001656068,0.0002054456,0.0001940838,0.000305037,0.000301401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004964574,"about_ca_system_score_gemma":0.0002759066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001008402,"about_ca_topic_score_gemma":0.0008972783,"domain_scores_codex":[0.9998381,0.00003098325,0.00001387023,0.00003102648,0.00006751719,0.00001851757],"domain_scores_gemma":[0.9998764,0.0000253641,0.00002606652,0.0000100066,0.00003981118,0.00002235413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005339843,0.000008146408,0.0002740393,0.00002469343,0.000002026703,0.00005080214,0.00001316668,0.0001330111,0.9990375,0.00005759206,0.00001323693,0.0003323854],"study_design_scores_gemma":[0.000009917452,0.0001182536,0.006278232,0.00001070209,0.00001286149,0.000418808,0.00006890001,0.002337278,0.9864354,0.00004681504,0.004258089,0.000004873352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955986,0.0006960286,0.002421458,0.00004644751,0.00001141261,0.00001722274,0.0004228826,0.00001561539,0.0007702634],"genre_scores_gemma":[0.992789,0.0003558848,0.0033796,0.00005116525,0.000004401952,0.0000226453,0.0022673,0.00001888815,0.001111136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001008402,"threshold_uncertainty_score":0.003602087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01735974320898131,"score_gpt":0.260893140223462,"score_spread":0.2435333970144807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}