{"id":"W2053167514","doi":"10.1046/j.1471-4159.2000.0750812.x","title":"Preconditioning with Cortical Spreading Depression Decreases Intraischemic Cerebral Glutamate Levels and Down‐Regulates Excitatory Amino Acid Transporters EAAT1 and EAAT2 from Rat Cerebal Cortex Plasma Membranes","year":2000,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Cortical spreading depression; Glutamate receptor; Ischemia; Cerebral cortex; Microdialysis; Internal medicine; Endocrinology; Chemistry; Transporter; Cortex (anatomy); Glutamic acid; Neuroscience; Biology; Biochemistry; Central nervous system; Amino acid; Medicine; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008559435,0.0005662526,0.0003717126,0.0002059147,0.0001069522,0.0002231794,0.0001504671,0.0002001373,0.0009420207],"category_scores_gemma":[0.0001205318,0.0001454262,0.0003455358,0.0001412079,0.0003124764,0.0001977327,0.0002044796,0.0006072028,0.0002214859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002345791,"about_ca_system_score_gemma":0.0002280548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001134248,"about_ca_topic_score_gemma":0.001639065,"domain_scores_codex":[0.9999099,0.0000069235,0.000008689366,0.00001928681,0.00002035281,0.00003485811],"domain_scores_gemma":[0.9998944,0.000007848794,0.00003786421,0.00001345301,0.00001732238,0.00002909062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002579008,0.00003021837,0.000187588,0.00002906644,0.00000788552,0.00002433985,0.00001327238,0.00001675708,0.9984699,0.00001440829,0.00001515498,0.0009335144],"study_design_scores_gemma":[0.00003582082,0.0009820421,0.02829156,0.000008039522,0.00004377372,0.0002021002,0.00006446825,0.0004385591,0.9694526,0.00004138693,0.0004330843,0.000006572821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978583,0.0009408289,0.0006896887,0.00004944139,0.00001588789,0.000009795246,0.00009804924,0.00003093529,0.0003069668],"genre_scores_gemma":[0.9961671,0.001240866,0.001037085,0.00005763541,0.00001239766,0.00003755422,0.000361121,0.00001104881,0.001075192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001134248,"threshold_uncertainty_score":0.003151357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01947630287454783,"score_gpt":0.2652757488243194,"score_spread":0.2457994459497716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}