{"id":"W2053184601","doi":"10.1371/journal.ppat.1001016","title":"Rabies Virus Infection Induces Type I Interferon Production in an IPS-1 Dependent Manner While Dendritic Cell Activation Relies on IFNAR Signaling","year":2010,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McGill University; National Institutes of Health; Thomas Jefferson University; National Institute of Allergy and Infectious Diseases; Ohio State University","keywords":"Biology; Rabies virus; Virology; Interferon; Interferon type I; Viral replication; Virus; Receptor; Cell biology; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002648697,0.0002168181,0.0002193338,0.000355956,0.0001884937,0.00003923177,0.0001286645,0.0003264791,0.0003735541],"category_scores_gemma":[0.0002354091,0.0002002723,0.00005076889,0.0001604294,0.0000855301,0.0003093795,0.00004720933,0.0007264483,0.0004821746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007510183,"about_ca_system_score_gemma":0.00004560899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001043764,"about_ca_topic_score_gemma":0.0004111674,"domain_scores_codex":[0.9985747,0.0003432499,0.0003095108,0.0004059623,0.00006087784,0.0003057289],"domain_scores_gemma":[0.9993198,0.00008594686,0.0001191338,0.0003130264,0.0001412296,0.00002087281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009692799,0.0006304643,0.001855348,0.00002674301,0.00002874923,0.000003505215,0.001762782,0.00005132209,0.9930205,0.00006103409,0.00007728457,0.001512939],"study_design_scores_gemma":[0.0003880724,0.001084897,0.01038544,0.0000959016,0.00002762482,0.00001822475,0.0005345245,0.000006157945,0.9866789,0.00004811855,0.0005101009,0.0002220246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970375,0.0001071548,0.000008604013,0.0001271575,0.001901697,0.0002976081,0.000009566347,0.000110232,0.0004004842],"genre_scores_gemma":[0.9985578,0.00007103566,0.00003378574,0.00007319547,0.0001128894,0.00004677676,0.0001062104,0.00003241827,0.0009658662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008530096,"threshold_uncertainty_score":0.8166866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02819772689695885,"score_gpt":0.2507339972844354,"score_spread":0.2225362703874766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}