{"id":"W2053202233","doi":"10.1007/s10719-006-7153-x","title":"UDP-Gal: GlcNAc-R β1,4-galactosyltransferase—a target enzyme for drug design. Acceptor specificity and inhibition of the enzyme","year":2006,"lang":"en","type":"article","venue":"Glycoconjugate Journal","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Arthritis Society","keywords":"Aglycone; Chemistry; Stereochemistry; Glycolipid; Galactosyltransferase; Enzyme; Glycan; Transferase; Glycoconjugate; Glycosyltransferase; Acceptor; Random hexamer; Glycosidic bond; Glycosyl; Biochemistry; Glycoside; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007648484,0.0002213049,0.0002304533,0.00009083499,0.0003398082,0.0001154576,0.0002354261,0.0001649055,0.0002140483],"category_scores_gemma":[0.0001327798,0.0001659479,0.0002172192,0.0001315409,0.000186754,0.00002502767,0.00007546785,0.0002862964,0.000004807141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003486357,"about_ca_system_score_gemma":0.000180297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004713228,"about_ca_topic_score_gemma":0.00005195847,"domain_scores_codex":[0.9982176,0.0002261833,0.0004957046,0.0003070463,0.0003514496,0.0004019942],"domain_scores_gemma":[0.9990138,0.00005593032,0.0002017802,0.0002772748,0.0003133591,0.000137871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005607437,0.0001022356,0.000922001,0.00003896826,0.00003789183,0.000003683748,0.00005365238,0.0004328424,0.981502,0.0002043006,0.01556376,0.0005779529],"study_design_scores_gemma":[0.001813846,0.0002617405,0.002305875,0.00002872207,0.00001985775,0.00008113842,0.00006179482,0.0002963227,0.9439673,0.001173019,0.0497912,0.0001991847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.943521,0.0008376931,0.05223043,0.001280156,0.000276553,0.001065935,0.0001244074,0.00001339224,0.0006504282],"genre_scores_gemma":[0.9950296,0.0001807001,0.002783528,0.0001439035,0.0007236492,0.00003840297,0.00005977093,0.00003452651,0.001005864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05150865,"threshold_uncertainty_score":0.6767158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01290270037589901,"score_gpt":0.2450402062238131,"score_spread":0.2321375058479141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}