{"id":"W2053202233","doi":"10.1007/s10719-006-7153-x","title":"UDP-Gal: GlcNAc-R β1,4-galactosyltransferase—a target enzyme for drug design. Acceptor specificity and inhibition of the enzyme","year":2006,"lang":"en","type":"article","venue":"Glycoconjugate Journal","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Arthritis Society","keywords":"Aglycone; Chemistry; Stereochemistry; Glycolipid; Galactosyltransferase; Enzyme; Glycan; Transferase; Glycoconjugate; Glycosyltransferase; Acceptor; Random hexamer; Glycosidic bond; Glycosyl; Biochemistry; Glycoside; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002880816,0.0005247284,0.000310793,0.000227656,0.0001281196,0.0004362479,0.0002872767,0.000300076,0.0006351047],"category_scores_gemma":[0.0001264087,0.0001506573,0.0001867754,0.00022799,0.0002735182,0.0003112404,0.0002115238,0.0007599153,0.0005710517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005671916,"about_ca_system_score_gemma":0.0002870705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005936125,"about_ca_topic_score_gemma":0.0006020445,"domain_scores_codex":[0.999923,0.00001972024,0.000003978357,0.00001137699,0.00002679866,0.0000151707],"domain_scores_gemma":[0.9999685,0.00000324764,0.000005505519,0.000003493566,0.000009003646,0.00001020116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006042119,0.0001066411,0.0004078533,0.0001419885,0.00001675733,0.0001298053,0.00001950032,0.0009119143,0.9487485,0.003158197,0.001238198,0.04451658],"study_design_scores_gemma":[0.00005568938,0.0004469979,0.0005260738,0.0000104382,0.00002028308,0.000390204,0.000009523369,0.00146562,0.9835955,0.0004491512,0.01302464,0.000005840202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7947809,0.0744018,0.09441295,0.003645927,0.0009347652,0.0003821666,0.001153369,0.0006137898,0.0296743],"genre_scores_gemma":[0.9625078,0.01793355,0.008884575,0.0002736842,0.00006474011,0.00004782312,0.0006287494,0.00003269774,0.009626422],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006351047,"threshold_uncertainty_score":0.004115343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01290270037589901,"score_gpt":0.2450402062238131,"score_spread":0.2321375058479141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}