{"id":"W2053210596","doi":"10.1038/mt.2013.263","title":"Morpholino Treatment Improves Muscle Function and Pathology of Pitx1 Transgenic Mice","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; National Institute of Child Health and Human Development; U.S. Department of Defense","keywords":"Morpholino; Facioscapulohumeral muscular dystrophy; In vivo; Genetically modified mouse; Muscular dystrophy; Biology; Zebrafish; Phenotype; Transgene; Cell biology; Pathology; Molecular biology; Cancer research; Medicine; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003815137,0.0001403793,0.0001415956,0.00002890763,0.00003808415,0.00000572767,0.00006929351,0.0001394635,0.00005084604],"category_scores_gemma":[0.000004457061,0.0001186351,0.00009304715,0.00003810615,0.0001121825,0.000003707117,0.00001472684,0.0000358158,0.000007951766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003567241,"about_ca_system_score_gemma":0.00002067444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008107042,"about_ca_topic_score_gemma":0.000006552739,"domain_scores_codex":[0.9993201,0.00007314224,0.0001327928,0.0002710665,0.00004085004,0.0001620635],"domain_scores_gemma":[0.9996315,0.000005960506,0.00005077407,0.0002337177,0.00003858468,0.00003944604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001876023,0.0001200916,0.0002303297,0.000006093017,0.00007887447,6.063291e-7,0.00005162394,0.000008803446,0.9632476,0.00005899919,0.00006073613,0.03594866],"study_design_scores_gemma":[0.002365426,0.003247005,0.07869426,0.000002649412,0.00002623207,0.00000563817,0.00007254303,0.00002879793,0.9077495,0.001495605,0.006106087,0.0002062974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931594,0.004381391,0.001766287,0.0001345958,0.00007356126,0.0002770992,0.000004817392,0.000008809367,0.0001940033],"genre_scores_gemma":[0.9972685,0.001585217,0.0002048798,0.0006756237,0.00003522404,0.00007688754,0.00005551584,0.00001714205,0.00008103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07846393,"threshold_uncertainty_score":0.48378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006410166756941097,"score_gpt":0.2128360846671761,"score_spread":0.206425917910235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}