{"id":"W2053210596","doi":"10.1038/mt.2013.263","title":"Morpholino Treatment Improves Muscle Function and Pathology of Pitx1 Transgenic Mice","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; National Institute of Child Health and Human Development; U.S. Department of Defense","keywords":"Morpholino; Facioscapulohumeral muscular dystrophy; In vivo; Genetically modified mouse; Muscular dystrophy; Biology; Zebrafish; Phenotype; Transgene; Cell biology; Pathology; Molecular biology; Cancer research; Medicine; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001678572,0.0006756532,0.000376718,0.0005047457,0.0001555647,0.0001890028,0.0002808331,0.0005362902,0.001413446],"category_scores_gemma":[0.0001087832,0.0002450195,0.0002960745,0.0001115153,0.00033337,0.0002488526,0.0001813793,0.0008595147,0.0002864764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002400459,"about_ca_system_score_gemma":0.0001936292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004665518,"about_ca_topic_score_gemma":0.0006940849,"domain_scores_codex":[0.9998228,0.00001902551,0.00001824988,0.00006097123,0.00004297662,0.0000359167],"domain_scores_gemma":[0.9998212,0.00001786375,0.000069275,0.00001028741,0.00001422037,0.00006718059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009071262,0.00004140574,0.00008538331,0.00002163319,0.000003196591,0.00005124291,0.000008729594,0.00002877742,0.9989284,0.00004183521,0.00002536877,0.0006733252],"study_design_scores_gemma":[0.00006137092,0.001117197,0.005095521,0.00001279603,0.00003116222,0.0005300729,0.00002791095,0.0008635111,0.990022,0.00006125293,0.00216981,0.000007397583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993887,0.0008190638,0.003046363,0.0002092301,0.0000563681,0.0000604629,0.0005778287,0.0002793489,0.001064295],"genre_scores_gemma":[0.9822136,0.001358982,0.005432263,0.0002054341,0.00003307806,0.0001692869,0.001258277,0.0001082869,0.009220624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001413446,"threshold_uncertainty_score":0.004728436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006410166756941097,"score_gpt":0.2128360846671761,"score_spread":0.206425917910235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}