{"id":"W2053229995","doi":"10.1007/s10930-008-9147-y","title":"Single Molecule Assays Reveal Differences Between In Vitro and In Vivo Synthesized β-Galactosidase","year":2008,"lang":"en","type":"article","venue":"The Protein Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Winnipeg; University of Manitoba","funders":"","keywords":"In vivo; Enzyme; In vitro; Molecular biology; Biochemistry; Enzyme assay; Escherichia coli; Chemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002983597,0.0001087272,0.0001431259,0.00005148417,0.00007567144,0.00002233732,0.0001423027,0.00006890232,0.00000867888],"category_scores_gemma":[0.0001027279,0.00007882286,0.00003675421,0.00006546031,0.00006194122,0.000003597602,0.00005598403,0.0002084042,6.572714e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000128243,"about_ca_system_score_gemma":0.00003078546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001628468,"about_ca_topic_score_gemma":0.00001296975,"domain_scores_codex":[0.9992492,0.0001050139,0.0001984961,0.0001333733,0.0001018444,0.000212129],"domain_scores_gemma":[0.9997248,0.00002199743,0.0000503077,0.0001228058,0.00001625217,0.00006383352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000747095,0.00002357411,0.006982064,0.000005944027,0.000009769563,0.00002093043,0.0001161824,0.00001673589,0.9916884,7.438996e-7,0.0000237289,0.001037161],"study_design_scores_gemma":[0.0005055479,0.00009147622,0.02358766,0.00003860626,0.000005150407,0.0001464068,0.00004525228,0.00004722424,0.9751808,0.00009358741,0.0001459676,0.0001123441],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956018,0.001057593,0.002710425,0.0002812952,0.00002087844,0.0001570803,0.000003858087,0.000003500016,0.0001635222],"genre_scores_gemma":[0.9988864,0.000103249,0.0006967977,0.0000230661,0.0001480122,0.00001291659,0.000001183172,0.00001140602,0.0001169692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01660559,"threshold_uncertainty_score":0.3214303,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01487152391970035,"score_gpt":0.2530192963113063,"score_spread":0.238147772391606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}