{"id":"W2053248846","doi":"10.1074/jbc.m502347200","title":"Identification of the VirB4-VirB8-VirB5-VirB2 Pilus Assembly Sequence of Type IV Secretion Systems","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; European Commission; McMaster University","keywords":"Pilus; Secretion; Biology; Bacterial outer membrane; Agrobacterium tumefaciens; Cell biology; Virulence; Pilin; Type three secretion system; Biochemistry; Gene; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000434633,0.0001294235,0.0002574897,0.00001968238,0.00003486118,0.00001222107,0.0004813126,0.0004890077,0.00001635104],"category_scores_gemma":[0.0002863516,0.0000815819,0.0001605003,0.0001362335,0.0002392085,0.000005049231,0.0001244735,0.0001970976,0.000001567369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002518937,"about_ca_system_score_gemma":0.0000823606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003220862,"about_ca_topic_score_gemma":6.430039e-7,"domain_scores_codex":[0.9987177,0.00007083361,0.0007265111,0.0001761291,0.0001624444,0.0001463795],"domain_scores_gemma":[0.9982974,0.00001704428,0.0009707464,0.0003172421,0.0003487371,0.00004883995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001244662,0.00007807964,0.0008108303,0.00003684119,0.0000423049,7.893706e-7,0.000005986208,0.0001261107,0.9978566,0.00003375204,0.0001156874,0.0007685582],"study_design_scores_gemma":[0.0002491323,0.0003065313,0.001914275,0.00003696113,0.00002551403,0.000103285,0.0000364633,0.0001985308,0.9902718,0.00004719868,0.006714473,0.00009581508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979107,0.001118966,0.0001827669,0.0002586242,0.0002641248,0.0000798296,0.00002975989,0.00000361761,0.0001516144],"genre_scores_gemma":[0.9985656,0.0007131496,0.0001388453,0.00003027783,0.0004009391,0.000001576143,0.00001595859,0.000007295545,0.0001264298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007584773,"threshold_uncertainty_score":0.3771675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01936212350907737,"score_gpt":0.2545517624154255,"score_spread":0.2351896389063482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}