{"id":"W2053249591","doi":"10.1083/jcb.200706083","title":"Loss of ATRX leads to chromosome cohesion and congression defects","year":2008,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":164,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Western University","funders":"","keywords":"ATRX; Biology; Prometaphase; Mitosis; Microcephaly; Chromosome segregation; Chromatid; Metaphase; Cell biology; Genetics; Chromosome; Mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000540099,0.0003339804,0.0001524213,0.0002866797,0.0001236232,0.0001851855,0.0001536074,0.0002066056,0.001599001],"category_scores_gemma":[0.000105483,0.0001797597,0.0001262032,0.0001246013,0.000185757,0.0000860223,0.0002297929,0.0003062755,0.0003412064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001747522,"about_ca_system_score_gemma":0.0001361773,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006441717,"about_ca_topic_score_gemma":0.0009636148,"domain_scores_codex":[0.9999267,0.00000867762,0.000009977465,0.00001760283,0.00002290563,0.00001416183],"domain_scores_gemma":[0.9999073,0.00001872734,0.00003103781,0.00001185571,0.000004235696,0.00002683786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007458539,0.00002240818,0.000362011,0.00001665517,0.000009126125,0.0004416992,0.00001692196,0.0001082897,0.9972695,0.0001257958,0.00005826225,0.001494691],"study_design_scores_gemma":[0.00003269982,0.0002833267,0.0175628,0.00001112342,0.00004477824,0.004637113,0.00005662908,0.001360283,0.9727225,0.0001341227,0.003147613,0.000007015934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976019,0.0004408645,0.0006744664,0.00003030212,0.000007229911,0.000005476928,0.0001564039,0.00005551177,0.001027759],"genre_scores_gemma":[0.9956241,0.0005097582,0.000498453,0.00001603078,0.000003463208,0.00000870716,0.0003434799,0.00002218556,0.002973844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001599001,"threshold_uncertainty_score":0.005349219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009645354113471094,"score_gpt":0.2314284834586743,"score_spread":0.2217831293452032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}