{"id":"W2053289234","doi":"10.1089/08828240152716628","title":"HIV-1 DNA Burden in Peripheral Blood CD4 <sup>+</sup> Cells Influences Disease Progression, Antiretroviral Efficacy, and CD4 <sup>+</sup> T-Cell Restoration","year":2001,"lang":"en","type":"article","venue":"Viral Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"Peripheral blood mononuclear cell; Viral load; Virology; Lentivirus; Viral replication; Biology; Virus; Immunology; Immune system; Provirus; DNA; Antiretroviral therapy; Viral disease; Gene; Genome; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003092616,0.0002227591,0.0001907691,0.0003521162,0.00009031277,0.0004991985,0.0001280802,0.0002897931,0.001179187],"category_scores_gemma":[0.001094593,0.0001793333,0.00006078214,0.0002450405,0.0003638958,0.0002488208,0.0001297933,0.0003716507,0.0002637407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001616734,"about_ca_system_score_gemma":0.0001414696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002045494,"about_ca_topic_score_gemma":0.0002067317,"domain_scores_codex":[0.9997765,0.00009048184,0.00001092417,0.00004933112,0.00003893436,0.00003372947],"domain_scores_gemma":[0.9993033,0.0003401931,0.0002055547,0.0000334286,0.00003590462,0.00008151696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004068345,0.0006605606,0.2666259,0.0001561613,0.00009565586,0.0003460092,0.0001206663,0.0008517993,0.6798281,0.0002300603,0.0002453913,0.04677137],"study_design_scores_gemma":[0.0001010894,0.004607712,0.8457425,0.00002149043,0.0001029533,0.001546601,0.0001392599,0.00348153,0.1424265,0.0003509542,0.001461591,0.00001784289],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983169,0.0007773931,0.0003912185,0.00002011614,0.000003782689,0.000009230168,0.00006433285,0.00001469329,0.0004023965],"genre_scores_gemma":[0.998717,0.0002474883,0.0005060606,0.0000188212,0.000009826514,0.00001368036,0.000132953,0.000003057326,0.0003511814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001179187,"threshold_uncertainty_score":0.003944755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009438807378596236,"score_gpt":0.2544466418726103,"score_spread":0.2450078344940141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}