{"id":"W2053289234","doi":"10.1089/08828240152716628","title":"HIV-1 DNA Burden in Peripheral Blood CD4 <sup>+</sup> Cells Influences Disease Progression, Antiretroviral Efficacy, and CD4 <sup>+</sup> T-Cell Restoration","year":2001,"lang":"en","type":"article","venue":"Viral Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"Peripheral blood mononuclear cell; Viral load; Virology; Lentivirus; Viral replication; Biology; Virus; Immunology; Immune system; Provirus; DNA; Antiretroviral therapy; Viral disease; Gene; Genome; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003273166,0.0005650331,0.0006659169,0.0004615847,0.00048304,0.00009954257,0.0005264779,0.0005787832,0.0006113921],"category_scores_gemma":[0.0001548615,0.0004814426,0.0001432047,0.0004225501,0.001197622,0.0004514586,0.000348202,0.000847096,0.001432246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001465969,"about_ca_system_score_gemma":0.0002895761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005948923,"about_ca_topic_score_gemma":0.00002904425,"domain_scores_codex":[0.9958736,0.0009899733,0.0007129653,0.0009504613,0.0001499211,0.001323096],"domain_scores_gemma":[0.9986579,0.0001971534,0.0001943273,0.0006805042,0.0001158199,0.0001542626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.007749191,0.003582958,0.2892468,0.0001279579,0.0008991907,0.001776967,0.005786615,0.001384374,0.6517314,0.0003408644,0.003348132,0.03402551],"study_design_scores_gemma":[0.1118443,0.03314164,0.4490606,0.001187828,0.001449187,0.001391959,0.008472366,0.003046839,0.1727715,0.001189191,0.2105118,0.005932761],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833966,0.01381587,0.00001306474,0.0007758925,0.0001708961,0.0009919549,0.000155319,0.0001568668,0.0005235003],"genre_scores_gemma":[0.9931343,0.001565199,0.0001424046,0.0001136667,0.00010754,0.0001933974,0.0008332321,0.00004985971,0.003860362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4789599,"threshold_uncertainty_score":0.9997637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009438807378596236,"score_gpt":0.2544466418726103,"score_spread":0.2450078344940141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}