{"id":"W2053302853","doi":"10.1128/aac.04056-14","title":"Evaluation of α,β-Unsaturated Ketones as Antileishmanial Agents","year":2015,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Institute of Allergy and Infectious Diseases; National Institute on Minority Health and Health Disparities; Canadian Institutes of Health Research; Washington University in St. Louis; University of Texas at El Paso; National Institutes of Health; National Institute of General Medical Sciences","keywords":"Toxicity; Intracellular; Extracellular; Leishmania; Parasite hosting; Leishmaniasis; Chemistry; Intracellular parasite; Amastigote; Pharmacology; Biochemistry; Biology; Microbiology; Immunology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000202596,0.0003646052,0.0002738574,0.0002706556,0.0001178215,0.0001592377,0.0001832166,0.0001563014,0.001563416],"category_scores_gemma":[0.0001551847,0.00007215863,0.0001573347,0.0002359112,0.0001146322,0.000198851,0.00009793779,0.0002179517,0.0002264767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000149749,"about_ca_system_score_gemma":0.0001986112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001003616,"about_ca_topic_score_gemma":0.001933703,"domain_scores_codex":[0.9998908,0.00003017953,0.00001372016,0.0000152133,0.00002751423,0.00002257404],"domain_scores_gemma":[0.9998741,0.00001750213,0.00002170379,0.000007386426,0.00005394234,0.00002524338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000690373,0.0001248397,0.0005528501,0.0002701629,0.00001710807,0.000132076,0.00002771393,0.0003126765,0.9879405,0.00005879418,0.00006627748,0.009806654],"study_design_scores_gemma":[0.00009501066,0.008006288,0.005368325,0.00003749735,0.0001097311,0.000372087,0.00009517653,0.000449753,0.9791462,0.00003377989,0.006268465,0.00001772865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854278,0.01000193,0.001072097,0.00007056874,0.00003632411,0.0001120143,0.0004034429,0.00002748787,0.002848387],"genre_scores_gemma":[0.9886386,0.006862891,0.001870199,0.00007145168,0.00001932721,0.00004003445,0.0004845842,0.000005605405,0.002007315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001563416,"threshold_uncertainty_score":0.005230188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08956382655699162,"score_gpt":0.368036367527785,"score_spread":0.2784725409707934,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}