{"id":"W2053356709","doi":"10.1016/j.ajpath.2011.03.044","title":"NPAS3 Demonstrates Features of a Tumor Suppressive Role in Driving the Progression of Astrocytomas","year":2011,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Hôpital de l'Enfant-Jésus; University Health Network; Centre hospitalier de l'Université Laval; Hôtel-Dieu de Québec","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Fondation CHU de Québec; University of Toronto; Harvard University; Canada Foundation for Innovation; Université Laval; Centre Hospitalier Universitaire de Québec","keywords":"Astrocytoma; Biology; Tumor progression; Pathology; Medicine; Cancer research; Glioma; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001219947,0.0001874382,0.0001648775,0.0002844922,0.0003479941,0.0003842177,0.0002352453,0.0002546444,0.002060181],"category_scores_gemma":[0.0002664675,0.0001212912,0.0002241768,0.0001946221,0.0002810329,0.0002226073,0.0001488193,0.0004887632,0.0004597396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003760138,"about_ca_system_score_gemma":0.0003644344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002653961,"about_ca_topic_score_gemma":0.003403196,"domain_scores_codex":[0.9999069,0.000007630775,0.000007199129,0.00001404012,0.00003848629,0.00002575016],"domain_scores_gemma":[0.999899,0.00001379745,0.00001602967,0.00001817362,0.00002241847,0.00003059137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000218115,0.00004361734,0.004350321,0.00002422952,0.00001178004,0.0006869864,0.00002791566,0.0001948556,0.988255,0.0007888027,0.0002095102,0.005188928],"study_design_scores_gemma":[0.00004125502,0.0003848625,0.09304886,0.000005610679,0.00004709531,0.01049342,0.000174791,0.003758548,0.8816429,0.001389633,0.008999563,0.00001346716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932561,0.0004513495,0.001312436,0.0001932416,0.00002478675,0.00001097544,0.0002735545,0.00009078886,0.004386799],"genre_scores_gemma":[0.9979529,0.00012312,0.0005426398,0.00003291219,0.000005334709,0.000006662901,0.0002389696,0.00001100299,0.001086432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002653961,"threshold_uncertainty_score":0.006891966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009716085442537555,"score_gpt":0.2721214264481133,"score_spread":0.2624053410055757,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}