{"id":"W2053384841","doi":"10.1007/s12015-011-9259-1","title":"Stem Cell Clinical Trials for Spinal Cord Injury: Readiness, Reluctance, Redefinition","year":2011,"lang":"en","type":"article","venue":"Stem Cell Reviews and Reports","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"NeuroDevNet; University of British Columbia","funders":"National Key Research and Development Program of China Stem Cell and Translational Research; Canadian Institutes of Health Research; Centre National d’Etudes Spatiales; Michael Smith Health Research BC; Stem Cell Network","keywords":"Clinical trial; Spinal cord injury; Medicine; Stem cell; Stem-cell therapy; Translational research; Clinical research; Informed consent; Physical therapy; Physical medicine and rehabilitation; Intensive care medicine; Spinal cord; Alternative medicine; Psychiatry; Surgery; Pathology; Transplantation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.4038274,0.0006660485,0.001857846,0.00237792,0.004170636,0.01599041,0.004929778,0.03419797,0.002570328],"category_scores_gemma":[0.4401102,0.001102077,0.001716171,0.002368668,0.02444677,0.01313855,0.009010392,0.03867508,0.00113976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005836487,"about_ca_system_score_gemma":0.03582367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001399231,"about_ca_topic_score_gemma":0.002938642,"domain_scores_codex":[0.7519739,0.1507236,0.02681676,0.008041376,0.05713998,0.005304468],"domain_scores_gemma":[0.2974281,0.6146194,0.0281671,0.01422442,0.03574763,0.00981335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003425582,0.0002508243,0.004008195,0.003325431,0.0001968528,0.001002434,0.01348917,0.0006448114,0.003540812,0.5695339,0.2021282,0.2015369],"study_design_scores_gemma":[0.0002982075,0.0005695521,0.003424158,0.007211244,0.0001642387,0.001947208,0.004708251,0.001258225,0.003042912,0.2301316,0.7470037,0.0002407712],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.005973933,0.04845706,0.007935564,0.9212618,0.004901171,0.0001262869,0.00003523239,0.000102188,0.01120686],"genre_scores_gemma":[0.201733,0.03436899,0.02031244,0.7213532,0.01182065,0.000824169,0.0001086933,0.0002596498,0.009219232],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.965802,"threshold_uncertainty_score":0.735187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3617624784781854,"score_gpt":0.449294554877913,"score_spread":0.0875320763997276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}