{"id":"W2053384841","doi":"10.1007/s12015-011-9259-1","title":"Stem Cell Clinical Trials for Spinal Cord Injury: Readiness, Reluctance, Redefinition","year":2011,"lang":"en","type":"article","venue":"Stem Cell Reviews and Reports","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"NeuroDevNet; University of British Columbia","funders":"National Key Research and Development Program of China Stem Cell and Translational Research; Canadian Institutes of Health Research; Centre National d’Etudes Spatiales; Michael Smith Health Research BC; Stem Cell Network","keywords":"Clinical trial; Spinal cord injury; Medicine; Stem cell; Stem-cell therapy; Translational research; Clinical research; Informed consent; Physical therapy; Physical medicine and rehabilitation; Intensive care medicine; Spinal cord; Alternative medicine; Psychiatry; Surgery; Pathology; Transplantation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01057824,0.0002171632,0.001333851,0.0000703456,0.0001176615,0.00001847454,0.00004486557,0.0004428539,0.00006714038],"category_scores_gemma":[0.0001022223,0.0001321751,0.0004298794,0.0001634433,0.0002939746,0.00004838416,0.00003377285,0.0003047531,0.00001142039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002166901,"about_ca_system_score_gemma":0.0001504822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001233174,"about_ca_topic_score_gemma":0.000002141642,"domain_scores_codex":[0.9959819,0.0003528997,0.002628174,0.0005349247,0.000268338,0.0002337932],"domain_scores_gemma":[0.9972786,0.0001341963,0.001645815,0.0004690273,0.000173877,0.0002985037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00160187,0.000355765,0.001009705,0.00393942,0.00003975588,0.0001498398,0.00009793266,8.108538e-9,0.001539104,0.001542809,0.01818987,0.9715339],"study_design_scores_gemma":[0.001139706,0.003329549,0.002717797,0.001696869,0.0006062656,0.0002532024,0.00007760642,0.00001814637,0.001803747,0.003186702,0.9848913,0.0002790952],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2442321,0.5066465,0.0102,0.007460792,0.02024994,0.0292809,0.0001134706,0.0005014349,0.1813149],"genre_scores_gemma":[0.8584636,0.1184118,0.005527924,0.000956075,0.001433548,0.0002620495,0.0001386934,0.00006740983,0.01473891],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9712548,"threshold_uncertainty_score":0.5389945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3617624784781854,"score_gpt":0.449294554877913,"score_spread":0.0875320763997276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}