{"id":"W2053390057","doi":"10.1016/j.atherosclerosis.2006.03.019","title":"Effect of individualizing starting doses of a statin according to baseline LDL-cholesterol levels on achieving cholesterol targets: The Achieve Cholesterol Targets Fast with Atorvastatin Stratified Titration (ACTFAST) study","year":2006,"lang":"en","type":"article","venue":"Atherosclerosis","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Heart Research Centre; University of Toronto; St. Michael's Hospital; Pfizer (Canada)","funders":"Pfizer","keywords":"Atorvastatin; Statin; Ldl cholesterol; Medicine; Cholesterol; Internal medicine; Washout; Urology; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002658912,0.002448142,0.004967109,0.0003837863,0.0006021492,0.001089585,0.00122879,0.002561898,0.00368728],"category_scores_gemma":[0.004592952,0.001319444,0.003122183,0.0005054983,0.0009504519,0.001325228,0.0008245289,0.003937241,0.0007623426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009199765,"about_ca_system_score_gemma":0.001306809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00642923,"about_ca_topic_score_gemma":0.006180861,"domain_scores_codex":[0.9985043,0.0007763528,0.0001065588,0.0002926924,0.0001073755,0.0002128584],"domain_scores_gemma":[0.9969155,0.001251709,0.0004707233,0.0005186759,0.00009008913,0.000753297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9675607,0.0114752,0.002205037,0.0001242178,0.001631431,0.00001850426,0.00006694035,0.0008293785,0.0008720174,0.00006006557,0.0005598185,0.01459678],"study_design_scores_gemma":[0.7780865,0.1732036,0.03798063,0.00007191813,0.005073661,0.00004221902,0.0001147012,0.00333458,0.0006650906,0.0005974936,0.0007333398,0.00009628291],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958994,0.0008962071,0.0003455018,0.0004894308,0.0003060006,0.0003240325,0.0005589896,0.00009104288,0.001089329],"genre_scores_gemma":[0.9941118,0.0009131538,0.001394825,0.0007156143,0.0003738687,0.0003827769,0.0006478211,0.00005078752,0.001409339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00642923,"threshold_uncertainty_score":0.01406187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01833880596673793,"score_gpt":0.2825080487898484,"score_spread":0.2641692428231105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}