{"id":"W2053519265","doi":"10.1016/j.cimid.2010.06.003","title":"Subcutaneous, but not intratracheal administration of the TLR9 agonist, CpG DNA transiently reduces parainfluenza-3 virus shedding in newborn lambs","year":2010,"lang":"en","type":"article","venue":"Comparative Immunology Microbiology and Infectious Diseases","topic":"Respiratory viral infections research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of Saskatchewan; Canadian Food Inspection Agency","funders":"National Institute of Allergy and Infectious Diseases","keywords":"CpG Oligodeoxynucleotide; TLR9; Biology; CpG site; Virus; Systemic administration; Virology; Immunology; Innate immune system; Viral shedding; Immunity; Respiratory system; Immune system; Gene; Gene expression; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002155498,0.0002781799,0.0006007092,0.0002684138,0.0003329526,0.00002798182,0.0001802915,0.0003572814,0.0001591177],"category_scores_gemma":[0.0002248668,0.000211924,0.0001420394,0.0003745506,0.002322292,0.0001449217,0.00007642713,0.0009770924,0.00001717704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007187851,"about_ca_system_score_gemma":0.0004418963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000104177,"about_ca_topic_score_gemma":0.001146781,"domain_scores_codex":[0.9979979,0.0005077551,0.0005776897,0.0004422439,0.00006722004,0.0004071784],"domain_scores_gemma":[0.9988137,0.0003250698,0.000204664,0.0003740627,0.0001897686,0.00009274061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002134094,0.000577034,0.06908483,0.00003336311,0.0002084751,0.00003206235,0.0003135656,0.000007164028,0.9257008,0.0008637366,0.0001015823,0.0009432387],"study_design_scores_gemma":[0.001961537,0.002356988,0.3224382,0.00005150185,0.0001281981,0.001609663,0.0002262334,0.00002738626,0.6680154,0.0002104075,0.002747858,0.000226642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965228,0.0009553054,0.0000248631,0.0002724823,0.0004272775,0.0007305547,0.0001334259,0.00005818535,0.0008751454],"genre_scores_gemma":[0.9992885,0.00008950899,0.00002660555,0.0002732898,0.00007462632,0.0001039472,0.00005280876,0.00001483096,0.00007586107],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2576855,"threshold_uncertainty_score":0.8642009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02334193202371114,"score_gpt":0.3249479643624073,"score_spread":0.3016060323386962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}