{"id":"W2053522089","doi":"10.1021/bi049496d","title":"Substrate Binding Affinity of <i>Pseudomonas aeruginosa </i>Membrane-Bound Lytic Transglycosylase B by Hydrogen−Deuterium Exchange MALDI MS","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Peptidoglycan; Chemistry; Dipeptide; Hydrogen–deuterium exchange; Stereochemistry; Bacterial cell structure; Biochemistry; Enzyme; Amino acid; Mass spectrometry; Bacteria; Chromatography; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002259491,0.0004883375,0.0003019106,0.0001988205,0.0001932436,0.0004220403,0.0003845468,0.0004428669,0.002276409],"category_scores_gemma":[0.0003550368,0.0002158529,0.0001873506,0.0001967131,0.0001465259,0.0001963668,0.0001881071,0.0004480402,0.0009887933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004696431,"about_ca_system_score_gemma":0.0001680989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002813281,"about_ca_topic_score_gemma":0.002219673,"domain_scores_codex":[0.9996803,0.00003874183,0.00001467911,0.00009893988,0.0001167655,0.00005056932],"domain_scores_gemma":[0.9998713,0.00004461604,0.00002033102,0.000009945724,0.00003192898,0.00002184333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002829499,0.000007823639,0.0001260923,0.00001616255,0.00000206777,0.000006413316,0.000007546161,0.00005654075,0.9991727,0.00001266181,0.00002450474,0.0005390772],"study_design_scores_gemma":[0.000003285061,0.00006233211,0.002770068,0.000004089378,0.000004764232,0.00004852763,0.00002312993,0.00218935,0.9941124,0.00001140516,0.0007645281,0.000006047243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882677,0.001002754,0.007729597,0.0001044868,0.00001545378,0.00002817583,0.0007160871,0.000187025,0.001948741],"genre_scores_gemma":[0.9865533,0.0007128664,0.008553077,0.00009142241,0.000006271843,0.00004152567,0.001025335,0.00005699525,0.002959209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002813281,"threshold_uncertainty_score":0.007615387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008574455465730555,"score_gpt":0.2144504706152419,"score_spread":0.2058760151495114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}