{"id":"W2053558836","doi":"10.1016/j.mrgentox.2004.06.005","title":"The potent colon carcinogen, 1,2-dimethylhydrazine induces mutations primarily in the colon","year":2004,"lang":"en","type":"article","venue":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"ca_institutions":"York University","funders":"National Cancer Institute; York University","keywords":"1,2-Dimethylhydrazine; Mutant; Carcinogen; Colorectal cancer; Dimethylhydrazine; Micronucleus test; Small intestine; Large intestine; Mutation frequency; Chemistry; Molecular biology; Cancer research; Biology; Internal medicine; Cancer; Medicine; Biochemistry; Genetics; Gene; Toxicity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002009392,0.0003771353,0.0002759823,0.0008373859,0.0001711019,0.0002083846,0.0001908798,0.0003808688,0.001632897],"category_scores_gemma":[0.0002161488,0.0003383455,0.0002180299,0.0002748645,0.0003127249,0.0001933798,0.0002885154,0.0002903479,0.000477248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002774939,"about_ca_system_score_gemma":0.0003687993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00195043,"about_ca_topic_score_gemma":0.002879402,"domain_scores_codex":[0.9998133,0.00004648746,0.00001088695,0.00004893301,0.00004280405,0.00003768509],"domain_scores_gemma":[0.999696,0.00006091235,0.0000886562,0.00005009539,0.00004272147,0.00006170164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007012667,0.000005712826,0.0003401423,0.0000119567,0.000002444815,0.00002881898,0.000004968191,0.00001636806,0.9990956,0.00003048571,0.00001213935,0.0003811185],"study_design_scores_gemma":[0.00001347811,0.0003680902,0.0172323,0.000004384038,0.00001887581,0.0006205392,0.00002825069,0.0001882506,0.9803079,0.00005500261,0.001159352,0.000003544122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99019,0.002085221,0.004344438,0.0001265953,0.00003577342,0.00005357611,0.0006451228,0.0002082654,0.002311078],"genre_scores_gemma":[0.9914576,0.001373929,0.00248177,0.00004254274,0.00001014247,0.00002764449,0.0004537291,0.00003559576,0.004116908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00195043,"threshold_uncertainty_score":0.005462587,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02041050703550244,"score_gpt":0.2974873787006405,"score_spread":0.277076871665138,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}