{"id":"W2053585778","doi":"10.1007/s10495-012-0723-4","title":"A genome wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance","year":2012,"lang":"en","type":"article","venue":"APOPTOSIS","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research","keywords":"Anoikis; Small hairpin RNA; Gene knockdown; Biology; Programmed cell death; Cell biology; Cancer research; Cell culture; Apoptosis; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008945559,0.0002327128,0.0005412768,0.0002648528,0.0001523536,0.00003981201,0.0002209985,0.0001414772,0.0004238118],"category_scores_gemma":[0.0003984371,0.0002115235,0.0002415679,0.0004967286,0.0002654631,0.0002504585,0.0001524924,0.0002553236,0.00006388527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001617337,"about_ca_system_score_gemma":0.000195255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004751993,"about_ca_topic_score_gemma":0.00005414484,"domain_scores_codex":[0.9975612,0.00006071238,0.0005032861,0.0003477501,0.0007934224,0.0007335865],"domain_scores_gemma":[0.9983612,0.00005176604,0.0001862641,0.0006721915,0.0002532899,0.0004752653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001656552,0.000527187,0.03526605,0.0004038322,0.0003440828,0.00001332797,0.002399395,0.000002087127,0.9393283,0.00268072,0.01700958,0.0003688438],"study_design_scores_gemma":[0.005779427,0.0007664388,0.3584746,0.0005950707,0.0003466638,0.00007115628,0.003523717,0.00001847867,0.4755551,0.0005428722,0.1536203,0.0007062929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854993,0.001720185,0.0001613959,0.004298581,0.0001078339,0.0005216794,0.00005824141,0.00005446122,0.007578379],"genre_scores_gemma":[0.9796834,0.00005639812,0.001051602,0.0005010628,0.0002626474,0.00008681096,0.00003474412,0.00005308125,0.01827024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4637733,"threshold_uncertainty_score":0.8625677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01702273329734953,"score_gpt":0.283279080176805,"score_spread":0.2662563468794555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}