{"id":"W2053618218","doi":"10.3390/v2102169","title":"Inhibitors of the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B","year":2010,"lang":"en","type":"article","venue":"Viruses","topic":"Hepatitis C virus research","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Center for Research Resources; University of California, San Francisco; National Institutes of Health; Canadian Institutes of Health Research; Cancer Research Society","keywords":"NS5B; Ribavirin; Virology; Hepatitis C virus; Polymerase; RNA polymerase; RNA-dependent RNA polymerase; Virus; Pegylated interferon; RNA virus; Biology; RNA; Medicine; Hepacivirus; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003147091,0.0001858562,0.0003267416,0.0001772509,0.0001354417,0.00003042659,0.0003314858,0.0001658278,0.0008425523],"category_scores_gemma":[0.0007899854,0.0001331706,0.0001687645,0.0003791913,0.0003433848,0.0001470187,0.000224366,0.0006931593,0.0004161466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005296209,"about_ca_system_score_gemma":0.000330734,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01895601,"about_ca_topic_score_gemma":0.007915549,"domain_scores_codex":[0.9978269,0.0001068496,0.0004323277,0.0002930857,0.0009414094,0.0003994011],"domain_scores_gemma":[0.9984472,0.0001514332,0.0001351834,0.0008600556,0.0001591695,0.000246962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006586165,0.0001841801,0.1825875,0.00004025981,0.00005230583,0.00004809392,0.0001515401,5.334718e-7,0.7787799,0.0002641866,0.003427672,0.03439791],"study_design_scores_gemma":[0.0007165759,0.0001336673,0.06309678,0.00007676948,0.00004024436,0.00001531707,0.00001731008,0.00002517119,0.9072283,0.00006098217,0.02845737,0.0001315386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921066,0.0002945898,0.000008709207,0.000742504,0.0009192789,0.0004616257,0.0001371445,0.0001502425,0.005179333],"genre_scores_gemma":[0.9969317,0.0004372636,0.0001490469,0.001338254,0.0004365947,0.00003562778,0.000003286595,0.00008593294,0.000582282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1284484,"threshold_uncertainty_score":0.9875768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02542514342196812,"score_gpt":0.3120579194786088,"score_spread":0.2866327760566407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}