{"id":"W2053620536","doi":"10.1186/1471-2180-12-70","title":"RND type efflux pump system MexAB-OprM of pseudomonas aeruginosa selects bacterial languages, 3-oxo-acyl-homoserine lactones, for cell-to-cell communication","year":2012,"lang":"en","type":"article","venue":"BMC Microbiology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science; Colorado State University","keywords":"Quorum sensing; Autoinducer; Biology; Efflux; Homoserine; Pseudomonas aeruginosa; Microbiology; Mutant; Cell biology; Complementation; Bacteria; Biochemistry; Biofilm; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003160621,0.0002592884,0.0003798878,0.00005765807,0.0001051592,0.00001758271,0.0002852003,0.0003796355,0.00003433368],"category_scores_gemma":[0.00006453793,0.0002452814,0.0001173976,0.0001072283,0.00007870477,0.000008187151,0.0002238828,0.0000842703,0.00004183345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000347985,"about_ca_system_score_gemma":0.00009803133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001081933,"about_ca_topic_score_gemma":0.0001548893,"domain_scores_codex":[0.9985311,0.0002014222,0.00038631,0.0003368852,0.00003408748,0.0005101738],"domain_scores_gemma":[0.9988121,0.00007058217,0.0002355769,0.0005993113,0.0001634611,0.0001190147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005304513,0.000123142,0.001136289,0.0002470062,0.00003341439,2.701758e-7,0.00007925474,0.000002378908,0.9956907,0.00009927745,0.001979767,0.00007806242],"study_design_scores_gemma":[0.001054196,0.0004065806,0.0007801397,0.00002974451,0.00004542373,0.00004812379,0.0001107513,0.000002918475,0.9261522,4.206125e-7,0.07111086,0.0002585935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966465,0.001030424,0.0001510006,0.00002848508,0.000769574,0.0005785544,0.0002121275,0.00002892184,0.0005544537],"genre_scores_gemma":[0.9896375,0.00007672694,0.00682672,0.00009142675,0.0005734481,0.00001846854,0.002348044,0.00004656546,0.0003811117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06953844,"threshold_uncertainty_score":0.9999999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01029100711379844,"score_gpt":0.2382053870392926,"score_spread":0.2279143799254942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}