{"id":"W2053708694","doi":"10.1210/en.2003-0484","title":"Distinct Molecular Pathways Mediate Progesterone-Induced Growth Inhibition And Focal Adhesion","year":2003,"lang":"en","type":"article","venue":"Endocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Directorate for Biological Sciences; Institute of Genetics; National Medical Research Council; Nanyang Technological University; University of Washington","keywords":"Focal adhesion; Cyclin D1; MAPK/ERK pathway; Progesterone receptor; Cancer research; Biology; Cell growth; Cell biology; Cyclin D; Internal medicine; Endocrinology; Kinase; Signal transduction; Cell cycle; Estrogen receptor; Cell; Cancer; Breast cancer; Medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008508022,0.0005229052,0.0002887204,0.0002827502,0.0002719997,0.0003207597,0.0002121571,0.0002762991,0.001823527],"category_scores_gemma":[0.0001478578,0.0001612188,0.00039916,0.0001762499,0.0002092634,0.0003213229,0.0003511954,0.0005903448,0.0004410872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000437716,"about_ca_system_score_gemma":0.0002747744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009424413,"about_ca_topic_score_gemma":0.001298391,"domain_scores_codex":[0.9997999,0.00002450063,0.0000115488,0.00003052243,0.00005964949,0.00007394367],"domain_scores_gemma":[0.9999152,0.00001118066,0.00002950319,0.000008335674,0.00001980259,0.00001583366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001967944,0.00004617745,0.0004671997,0.0002524996,0.00001751895,0.000418883,0.00005220404,0.00005340228,0.9910348,0.0009027596,0.0001610061,0.006396853],"study_design_scores_gemma":[0.00006186692,0.0004379052,0.03112474,0.00002992879,0.00005647996,0.001505527,0.0001169769,0.001079228,0.9525021,0.0005444245,0.01252992,0.00001089241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9104995,0.0588279,0.01341666,0.001264782,0.0002385589,0.0003072028,0.001013919,0.0002456169,0.01418589],"genre_scores_gemma":[0.9754488,0.01462063,0.002244878,0.0001309589,0.00005140066,0.0001852415,0.0004863792,0.000009577395,0.006822219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001823527,"threshold_uncertainty_score":0.006100237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009151058700599823,"score_gpt":0.2246954547354254,"score_spread":0.2155443960348256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}