{"id":"W2053831749","doi":"10.1038/ncb3161","title":"Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages","year":2015,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":317,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Embryoid body; Hemangioblast; Embryonic stem cell; Biology; Cell biology; Notch signaling pathway; Haematopoiesis; Endothelium; Progenitor cell; Stem cell; CD34; Vasculogenesis; Induced pluripotent stem cell; Anatomy; Immunology; Genetics; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004146597,0.0002169069,0.0002313591,0.00007296795,0.000111025,0.00002804498,0.0003469122,0.0007133799,0.00004605602],"category_scores_gemma":[0.0007011855,0.0001812579,0.0001047094,0.0001103297,0.0005061153,0.000003540608,0.0003749193,0.0004509852,0.00004285106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002344821,"about_ca_system_score_gemma":0.0001355212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004204989,"about_ca_topic_score_gemma":0.00005240903,"domain_scores_codex":[0.9982404,0.0002195362,0.0002403169,0.0006836965,0.0001754477,0.0004406368],"domain_scores_gemma":[0.998744,0.00005938853,0.00008882525,0.0005581289,0.0001872708,0.000362423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007461436,0.000112397,0.00110224,0.00001351704,0.0000661978,0.000007790439,0.00002499785,4.233957e-7,0.9906529,0.0007036104,0.005845573,0.001395708],"study_design_scores_gemma":[0.002123503,0.000690728,0.002542146,0.000006370808,0.00003661372,0.00002516269,0.0000668476,0.00001578793,0.5083833,0.00183393,0.4839489,0.0003266229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787469,0.00625148,0.001215011,0.0009962358,0.0003806332,0.0006317417,0.0003486308,0.00005171877,0.01137766],"genre_scores_gemma":[0.9960195,0.0002607597,0.0005810937,0.0005021681,0.000935326,0.0001063343,0.0008347052,0.00002927701,0.0007308217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4822696,"threshold_uncertainty_score":0.7391481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01654839279219729,"score_gpt":0.3039856843608025,"score_spread":0.2874372915686052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}