{"id":"W2053844335","doi":"10.1210/me.2010-0334","title":"37-kDa Laminin Receptor Precursor Mediates GnRH-II–Induced MMP-2 Expression and Invasiveness in Ovarian Cancer Cells","year":2010,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"GNRHR; Matrigel; Laminin; Biology; Cell migration; Receptor; Small interfering RNA; Cancer research; Gene knockdown; Autocrine signalling; Molecular biology; Cell biology; Cell; Extracellular matrix; Transfection; Cell culture; Endocrinology; Gonadotropin-releasing hormone; Biochemistry; Angiogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000179529,0.0003134865,0.000533255,0.0003793774,0.00009785178,0.00002344924,0.0002842932,0.000324787,0.001072856],"category_scores_gemma":[0.0003933495,0.0002877206,0.00008267564,0.0003406405,0.0002231547,0.00006774048,0.0004845914,0.001055142,0.00009464766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007436579,"about_ca_system_score_gemma":0.0002726592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003635593,"about_ca_topic_score_gemma":0.0003707631,"domain_scores_codex":[0.9973375,0.0002454052,0.0003986284,0.000765695,0.0004007403,0.0008520184],"domain_scores_gemma":[0.9986485,0.0001671236,0.0001017631,0.0006146971,0.0001424975,0.0003254225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002485238,0.0002079709,0.007733087,0.00009206909,0.00003462881,0.0009191973,0.000308584,0.000002625122,0.9845833,0.0002271855,0.0004516458,0.00519121],"study_design_scores_gemma":[0.003042805,0.0003744492,0.01031074,0.00009603374,0.00002917658,0.0001210268,0.0000974763,0.00004220892,0.9782072,0.0001180178,0.007301681,0.0002591863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943603,0.0006552638,0.00004132433,0.002473037,0.0005604298,0.0008095601,0.00001415164,0.00005813853,0.00102776],"genre_scores_gemma":[0.9959416,0.0005640001,0.00181861,0.0004188435,0.0001205057,0.000306855,0.00004280034,0.00007156566,0.0007152021],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006850035,"threshold_uncertainty_score":0.9999575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01925876762929169,"score_gpt":0.3029493991335725,"score_spread":0.2836906315042808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}