{"id":"W2053854091","doi":"10.1055/s-2009-1216530","title":"Variability of In Vitro Macrophage Activation by Commercially Diverse Bulk Echinacea Plant Material is Due Predominantly to Bacterial Lipoproteins and Lipopolysaccharides","year":2009,"lang":"en","type":"article","venue":"Planta Medica","topic":"Herbal Medicine Research Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Drug Abuse; Agricultural Research Service; University of British Columbia; University of Illinois at Urbana-Champaign; National Oceanic and Atmospheric Administration; U.S. Food and Drug Administration; National Science Foundation of Sri Lanka; University of Colombo; U.S. Department of Agriculture; Western Carolina University; International Science Council; Chinese Academy of Sciences; Kurukshetra University; National Center for Complementary and Alternative Medicine; China Academy of Traditional Chinese Medicine; National Institutes of Health; National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Hong Kong Polytechnic University; National Science Foundation; Deutsche Krebshilfe; National Natural Science Foundation of China; Tata Trusts; University Grants Commission; Wake Forest University","keywords":"Macrophage; In vitro; Polymyxin B; Monocyte; Biology; Echinacea (animal); Traditional medicine; Biotechnology; Microbiology; Biochemistry; Immunology; Medicine; Antibiotics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002054143,0.0002819045,0.0004038575,0.0002080544,0.0002344177,0.0003923758,0.000231871,0.0003421613,0.002363626],"category_scores_gemma":[0.001190554,0.0001789356,0.0003591647,0.0002079644,0.0003166663,0.0001729904,0.0002280437,0.0006802509,0.000323299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001375237,"about_ca_system_score_gemma":0.0001923445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002430497,"about_ca_topic_score_gemma":0.0004608007,"domain_scores_codex":[0.9987689,0.0007707229,0.00008403436,0.0001094926,0.0001639849,0.0001028406],"domain_scores_gemma":[0.9991595,0.0004266016,0.0001101717,0.0001584187,0.00008903316,0.00005642112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02068919,0.003137791,0.00271577,0.0002261103,0.0001049638,0.00008186719,0.0001834645,0.000289115,0.9607828,0.0001638325,0.0002302328,0.01139489],"study_design_scores_gemma":[0.002684681,0.2007188,0.06115111,0.00006533936,0.000321143,0.0005686229,0.0002654978,0.001386449,0.7269654,0.0005331498,0.005311987,0.00002778096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955041,0.001191972,0.001884709,0.00007968696,0.00004803275,0.0002309533,0.0002095691,0.00001891326,0.000832144],"genre_scores_gemma":[0.9963078,0.0003936848,0.001170917,0.0001054304,0.00004400124,0.000243037,0.0004388271,0.00001374056,0.001282598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002363626,"threshold_uncertainty_score":0.01086348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01284108674574883,"score_gpt":0.2778601460131599,"score_spread":0.265019059267411,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}