{"id":"W2053855385","doi":"10.1016/j.cell.2009.04.019","title":"Dissociation of the Opioid Receptor Mechanisms that Control Mechanical and Heat Pain","year":2009,"lang":"en","type":"article","venue":"Cell","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":452,"is_retracted":false,"has_abstract":false,"ca_institutions":"AstraZeneca (Canada)","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Drug Abuse","keywords":"Receptor; Substance P; TRPV1; μ-opioid receptor; Neuroscience; Biology; Nociceptor; Inhibitory postsynaptic potential; Afferent; Opioid; Opioid receptor; δ-opioid receptor; Cell biology; Nociception; Neuropeptide; Transient receptor potential channel; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003066366,0.0002595291,0.0005725357,0.0004733302,0.0004587377,0.001128214,0.0008099558,0.0008230692,0.002592747],"category_scores_gemma":[0.0005624327,0.0003983807,0.0004483449,0.0001734551,0.0009897443,0.001872964,0.0005951628,0.002021849,0.0009633505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005101606,"about_ca_system_score_gemma":0.0005745498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001171046,"about_ca_topic_score_gemma":0.00161744,"domain_scores_codex":[0.9997783,0.00001615394,0.00001242735,0.000026247,0.00007567665,0.00009122324],"domain_scores_gemma":[0.9996982,0.00006720506,0.00004473655,0.00004570225,0.00006426974,0.00008007612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007397219,0.00005228209,0.0004928816,0.0001019845,0.00001703255,0.0001774973,0.0001276191,0.00007449544,0.9801016,0.009679349,0.0001592926,0.00827626],"study_design_scores_gemma":[0.0003353653,0.001096972,0.2075909,0.0002079752,0.0001135288,0.005701558,0.001447205,0.003012988,0.7441069,0.02085875,0.01545159,0.00007617295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9630184,0.01423582,0.008317498,0.00156186,0.0002247588,0.00004386844,0.0004482846,0.00007364006,0.01207587],"genre_scores_gemma":[0.9813029,0.004572495,0.003514175,0.000634585,0.000130997,0.00006711973,0.0008031919,0.0000420317,0.00893256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002592747,"threshold_uncertainty_score":0.008673608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01404182339391354,"score_gpt":0.2134238988413408,"score_spread":0.1993820754474272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}