{"id":"W2053855385","doi":"10.1016/j.cell.2009.04.019","title":"Dissociation of the Opioid Receptor Mechanisms that Control Mechanical and Heat Pain","year":2009,"lang":"en","type":"article","venue":"Cell","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":452,"is_retracted":false,"has_abstract":false,"ca_institutions":"AstraZeneca (Canada)","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Drug Abuse","keywords":"Receptor; Substance P; TRPV1; μ-opioid receptor; Neuroscience; Biology; Nociceptor; Inhibitory postsynaptic potential; Afferent; Opioid; Opioid receptor; δ-opioid receptor; Cell biology; Nociception; Neuropeptide; Transient receptor potential channel; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001231694,0.00006484637,0.0001064202,0.000009062025,0.00007059478,0.00001088271,0.0001250754,0.0000350158,0.00002673957],"category_scores_gemma":[0.0001221925,0.00004211188,0.00004566403,0.000054598,0.00003196444,0.00003776678,0.00002746847,0.00007752478,0.000008467118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006915013,"about_ca_system_score_gemma":0.000006604391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002735883,"about_ca_topic_score_gemma":4.183619e-7,"domain_scores_codex":[0.999333,0.0001870233,0.00009032135,0.0001719294,0.00009579898,0.0001219563],"domain_scores_gemma":[0.9996344,0.0001639753,0.00004955911,0.0001118569,0.000008702892,0.00003146876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000184907,0.00003403058,0.00001079783,0.000003757498,3.534441e-7,4.194989e-7,0.00002523062,0.00000223163,0.9931151,0.00582718,0.0002380812,0.0007242897],"study_design_scores_gemma":[0.0002574039,0.000270768,0.001219332,0.000006374097,0.000004271222,7.125162e-7,0.00001450076,0.000342734,0.9858742,0.01091286,0.001046791,0.00005010267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975542,0.00001990502,0.000514762,0.0006925177,0.0001702637,0.0002109523,0.00001256775,0.00002464821,0.0008002134],"genre_scores_gemma":[0.996448,0.00003223408,0.0000390506,0.003246461,0.00002888748,0.000001685221,3.481117e-7,0.000005172612,0.0001981926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007240986,"threshold_uncertainty_score":0.1717273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01404182339391354,"score_gpt":0.2134238988413408,"score_spread":0.1993820754474272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}