{"id":"W2053898412","doi":"10.1086/375372","title":"Age‐Related Immune Dysfunction in Health and in Human Immunodeficiency Virus (HIV) Disease: Association of Age and HIV Infection with Naive CD8<sup>+</sup>Cell Depletion, Reduced Expression of CD28 on CD8<sup>+</sup>Cells, and Reduced Thymic Volumes","year":2003,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":157,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Institute on Aging; National Institutes of Health","keywords":"Immunology; CD8; CD28; Disease; Immune system; Immunopathology; Medicine; Immunodeficiency; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003388181,0.0002980962,0.000250648,0.0004697577,0.0002013527,0.0002859634,0.0001525698,0.0004158619,0.0008674915],"category_scores_gemma":[0.0006688416,0.0001271002,0.00009462525,0.0003113651,0.0002382912,0.0003560749,0.0002928391,0.000275965,0.0001445802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00011792,"about_ca_system_score_gemma":0.0001029037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003974502,"about_ca_topic_score_gemma":0.0004938007,"domain_scores_codex":[0.9998714,0.00004790946,0.00001134693,0.00002787786,0.00001798739,0.00002350013],"domain_scores_gemma":[0.9996425,0.00006387749,0.0001602545,0.00001877103,0.00002469677,0.00008990026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001827248,0.0001986427,0.9797977,0.00006143293,0.00006251519,0.0007361089,0.000166007,0.00007522211,0.007648773,0.00006233605,0.0001076957,0.00925633],"study_design_scores_gemma":[0.00000611414,0.0005115114,0.9974267,0.000005996533,0.0000225755,0.001233765,0.00006341601,0.0001034201,0.0004080751,0.00005562097,0.0001601168,0.000002653867],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997871,0.001707269,0.00007730423,0.00001949549,0.00000492809,0.000004562087,0.00004838175,0.000002467345,0.0002645372],"genre_scores_gemma":[0.9992005,0.0004081664,0.000110761,0.00002399444,0.00001610745,0.00000455257,0.00007314322,7.600391e-7,0.0001620208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008674915,"threshold_uncertainty_score":0.002902031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006026991278642342,"score_gpt":0.2320376300453687,"score_spread":0.2260106387667264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}