{"id":"W2053898412","doi":"10.1086/375372","title":"Age‐Related Immune Dysfunction in Health and in Human Immunodeficiency Virus (HIV) Disease: Association of Age and HIV Infection with Naive CD8<sup>+</sup>Cell Depletion, Reduced Expression of CD28 on CD8<sup>+</sup>Cells, and Reduced Thymic Volumes","year":2003,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":157,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Institute on Aging; National Institutes of Health","keywords":"Immunology; CD8; CD28; Disease; Immune system; Immunopathology; Medicine; Immunodeficiency; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009397398,0.0002688222,0.0005707836,0.0005370982,0.00033966,0.00002773182,0.00008633716,0.0001524369,0.00004647856],"category_scores_gemma":[0.0003299112,0.0001915553,0.00009025612,0.0003639889,0.0002967757,0.0002228787,0.00004433931,0.0005001921,0.000004777114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002911735,"about_ca_system_score_gemma":0.000248418,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005451536,"about_ca_topic_score_gemma":0.0000580846,"domain_scores_codex":[0.9966799,0.00168192,0.0008344708,0.0002565542,0.0001826946,0.0003644688],"domain_scores_gemma":[0.9982634,0.0003554573,0.0008764532,0.0002265017,0.0001653659,0.0001128712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004343401,0.003204823,0.518477,0.0003879019,0.000369591,0.00004789281,0.004995383,0.007959468,0.4590062,0.00006421981,0.0003278104,0.0008163225],"study_design_scores_gemma":[0.01978727,0.006045695,0.9082105,0.001873326,0.0004450441,0.0002011372,0.002604135,0.0001472417,0.05923425,0.000742605,0.0002283724,0.0004804708],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897141,0.009392411,0.00002683684,0.00008878883,0.00005754977,0.0005459779,0.00006475601,0.00001896076,0.0000905678],"genre_scores_gemma":[0.9942913,0.005323343,0.000007736469,0.00001855413,0.00001082435,0.00001798243,0.00008482128,0.00002294709,0.0002224749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.399772,"threshold_uncertainty_score":0.7811397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006026991278642342,"score_gpt":0.2320376300453687,"score_spread":0.2260106387667264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}