{"id":"W2053902344","doi":"10.1158/1535-7163.targ-13-c70","title":"Abstract C70: A phase 2 study of intravenous administration of REOLYSIN® (reovirus type 3 dearing) in combination with paclitaxel (P) and carboplatin (C) in patients with squamous cell carcinoma of the lung.","year":2013,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"","keywords":"Medicine; Carboplatin; Oncolytic virus; Internal medicine; Chemotherapy; Regimen; Clinical endpoint; Oncology; Gastroenterology; Phases of clinical research; Rash; Paclitaxel; Clinical trial; Cancer; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005240822,0.0001111462,0.000157233,0.00005481943,0.00001503694,0.000006495377,0.00008246677,0.00005141372,0.000004194523],"category_scores_gemma":[0.000004562769,0.0000792902,0.00001790842,0.0001825797,0.00007111575,0.000006151539,0.00002854279,0.00007595072,5.700454e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003855055,"about_ca_system_score_gemma":0.0001612441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004048909,"about_ca_topic_score_gemma":0.002449379,"domain_scores_codex":[0.9992141,0.00005761916,0.0002118563,0.0001741624,0.0002122885,0.0001299838],"domain_scores_gemma":[0.9994065,0.000007907894,0.0001638043,0.0002348592,0.0001598541,0.00002711125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002543524,0.00378589,0.833036,0.0001131632,0.0001076845,0.000007272761,0.0009225773,0.0002444723,0.1548051,0.000003869335,0.000001640047,0.00442881],"study_design_scores_gemma":[0.008711948,0.005979645,0.7477059,0.00002589642,0.00004706006,5.486633e-7,0.0001939305,0.00008263579,0.2371513,0.00001098786,0.000003496601,0.000086684],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983518,0.000690957,0.00001181635,0.00001341726,0.00001104528,0.0008555955,0.00001900705,9.491574e-7,0.00004541413],"genre_scores_gemma":[0.9998448,0.0000231278,0.00002880702,0.00001477895,0.000002738565,0.00004605049,0.00001953171,0.00001501804,0.000005100611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0853301,"threshold_uncertainty_score":0.6120766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01092082922319129,"score_gpt":0.2704467142879798,"score_spread":0.2595258850647885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}