{"id":"W2053975578","doi":"10.1038/nsmb1079","title":"Structure and mechanism of a bacterial β-glucosaminidase having O-GlcNAcase activity","year":2006,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"Biotechnology and Biological Sciences Research Council; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Royal Society; Michael Smith Health Research BC","keywords":"Serine; Bacteroides thetaiotaomicron; Biochemistry; Threonine; Enzyme; Active site; Biology; Phosphorylation; Rational design; Hydrolase; Chemistry; Bacteroides; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002527722,0.0003388911,0.0002910671,0.0001788053,0.0003355971,0.0006963312,0.0006760045,0.0006524645,0.0004862035],"category_scores_gemma":[0.0002276616,0.0002557893,0.0004099841,0.0001759069,0.000551124,0.0004646338,0.0002642303,0.0007389333,0.0004568724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007497736,"about_ca_system_score_gemma":0.0004253365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001507545,"about_ca_topic_score_gemma":0.0004249948,"domain_scores_codex":[0.9999241,0.00001201675,0.000004977673,0.0000168188,0.00001635514,0.00002571271],"domain_scores_gemma":[0.9998606,0.00002516756,0.00003113932,0.00001972951,0.00001859081,0.00004477396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005989402,0.0001065453,0.001030472,0.0000994311,0.00001977366,0.0008928188,0.0001084216,0.00141031,0.9827703,0.00892581,0.0001773843,0.003859805],"study_design_scores_gemma":[0.00009273872,0.0007742221,0.007438014,0.00001915501,0.00004150342,0.001372654,0.0001854722,0.008667475,0.9736601,0.002915462,0.004801697,0.00003150736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904608,0.001748226,0.004804519,0.0003438988,0.00005082128,0.00003473367,0.00008819485,0.00005079449,0.002418062],"genre_scores_gemma":[0.99371,0.0008139198,0.002707635,0.00007513796,0.00001980818,0.00001799945,0.0002624751,0.000007834155,0.002385239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001507545,"threshold_uncertainty_score":0.005439937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003413737434284521,"score_gpt":0.2804737883886739,"score_spread":0.2770600509543894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}