{"id":"W2053991148","doi":"10.1021/ja9939688","title":"Influence of β-Sheet Structure on the Susceptibility of Proteins to Backbone Oxidative Damage:  Preference for <sup>α</sup>C-Centered Radical Formation at Glycine Residues of Antiparallel β-Sheets","year":2000,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Free Radicals and Antioxidants","field":"Chemistry","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Chemistry; Antiparallel (mathematics); Radical; Beta sheet; Protein secondary structure; Crystallography; Random coil; Hydrogen bond; Stereochemistry; Protein structure; Circular dichroism; Molecule; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002815572,0.0004331991,0.0002769178,0.0002096659,0.0002842755,0.0003224107,0.0002563728,0.0002684424,0.001281287],"category_scores_gemma":[0.0004789915,0.0002149625,0.0002787569,0.0001465925,0.0003233573,0.0002227914,0.0002501102,0.0003183502,0.0001624341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001582819,"about_ca_system_score_gemma":0.0001658419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005975734,"about_ca_topic_score_gemma":0.0007574388,"domain_scores_codex":[0.9999276,0.00002124289,0.000003235507,0.0000107529,0.00001860046,0.00001849024],"domain_scores_gemma":[0.9996841,0.000171616,0.00004662824,0.00001914021,0.0000335711,0.00004498174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001756258,0.0001817291,0.01590341,0.0007129166,0.0002574348,0.0009821904,0.0002477337,0.2176279,0.7484475,0.002371821,0.0002609419,0.01125021],"study_design_scores_gemma":[0.0002059724,0.002949314,0.04427339,0.00007164985,0.000330952,0.0005561145,0.0005029678,0.5213742,0.4244596,0.003838032,0.00134327,0.00009456408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982474,0.0002293048,0.0005898968,0.00001639958,0.000005198659,0.0000050081,0.00002444897,0.00001383056,0.0008684112],"genre_scores_gemma":[0.9994197,0.0001502338,0.0002835889,0.000007067733,0.000001860682,0.000004045669,0.00003390558,0.000006235337,0.00009323489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001281287,"threshold_uncertainty_score":0.004286349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01728971972813335,"score_gpt":0.2529237199757581,"score_spread":0.2356340002476248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}