{"id":"W2053999060","doi":"10.1016/j.ejps.2012.11.013","title":"Molecular mechanism depressing PMA-induced invasive behaviors in human lung adenocarcinoma cells by cis- and trans-cinnamic acid","year":2012,"lang":"en","type":"article","venue":"European Journal of Pharmaceutical Sciences","topic":"Phytochemical compounds biological activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Beef Cattle Research Council","keywords":"Chemistry; Matrix metalloproteinase; A549 cell; Adenocarcinoma; MAPK/ERK pathway; Cinnamic acid; Metastasis; Phorbol; Phytochemical; Blot; Molecular biology; Cancer research; Pharmacology; Enzyme; Signal transduction; Biochemistry; Cancer; Protein kinase C; Biology; Cell; Internal medicine; Medicine; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001086689,0.0001785475,0.000202061,0.00006686094,0.0001249727,0.00006117315,0.0004174643,0.00005719281,0.00001905936],"category_scores_gemma":[0.00006272727,0.00013843,0.00008588687,0.0001315291,0.0003557497,0.00004021334,0.0001557152,0.0003166404,0.000001135224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002283691,"about_ca_system_score_gemma":0.00002887581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001987702,"about_ca_topic_score_gemma":5.469675e-7,"domain_scores_codex":[0.9982163,0.0004846146,0.0003631656,0.000255041,0.0002499802,0.0004308603],"domain_scores_gemma":[0.9993869,0.00003814106,0.0001576887,0.00008601232,0.00003809138,0.0002931305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003603275,0.0001096099,0.003012662,0.000009604632,0.00001315319,0.00003738484,0.00007430772,0.000003896144,0.995874,0.00002618467,0.00005275106,0.0007504505],"study_design_scores_gemma":[0.0005222359,0.0004420843,0.001889076,0.00003380964,0.00003114667,0.00008727717,0.00008876585,0.00002871254,0.9964366,0.00009232912,0.0001609883,0.000186957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944057,0.003463925,0.001166251,0.0001383526,0.0001152379,0.00009114563,0.000004781763,0.000005157943,0.0006094009],"genre_scores_gemma":[0.9990215,0.0001145781,0.0004040085,0.0003161643,0.0001216799,0.000001272266,0.000002284006,0.00001356556,0.000004902035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004615799,"threshold_uncertainty_score":0.5645011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03650002936250953,"score_gpt":0.3177122496109,"score_spread":0.2812122202483905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}