{"id":"W2054088727","doi":"10.4161/15548627.2014.984270","title":"Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"Merck KGaA","keywords":"Autophagy; ATG5; BECN1; Biology; Cell biology; Autophagosome; Mitophagy; ATG12; Programmed cell death; Pharmacology; Biochemistry; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003316442,0.0002112973,0.0002942528,0.00007850384,0.0002007705,0.00002037008,0.0002120511,0.00009094327,0.0003200177],"category_scores_gemma":[0.0001159122,0.0001200974,0.0002700324,0.0004148977,0.0002155534,0.0001180679,0.00005106812,0.0003038705,0.00008681532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004982536,"about_ca_system_score_gemma":0.0001018529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005504319,"about_ca_topic_score_gemma":0.000009527416,"domain_scores_codex":[0.9983954,0.0002251188,0.0003627787,0.0002931339,0.000445748,0.0002778475],"domain_scores_gemma":[0.9985916,0.0001452386,0.0002396129,0.0008450752,0.00008416882,0.00009430403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001784211,0.001725131,0.008478093,0.0006799582,0.0006418635,0.00007165055,0.002149785,0.0005537576,0.867517,0.02486388,0.02478727,0.06674737],"study_design_scores_gemma":[0.003303216,0.0002782136,0.297369,0.0001592527,0.0002166385,0.0001016421,0.00008639297,0.001823929,0.6737289,0.003556341,0.01918463,0.0001918482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928633,0.0003519286,0.0002565384,0.002225451,0.0009831905,0.0006846525,0.000007590055,0.0001125053,0.002514817],"genre_scores_gemma":[0.9937471,0.00009454535,0.0000351087,0.003703036,0.0003419044,0.00003606896,0.00001267297,0.0000361067,0.001993509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2888909,"threshold_uncertainty_score":0.4897428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01384470069805358,"score_gpt":0.2708248959565757,"score_spread":0.2569801952585221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}