{"id":"W2054108096","doi":"10.1371/journal.pone.0013828","title":"Versican G3 Promotes Mouse Mammary Tumor Cell Growth, Migration, and Metastasis by Influencing EGF Receptor Signaling","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto; Health Sciences Centre","funders":"Canadian Breast Cancer Research Alliance; Barbara Ann Karmanos Cancer Institute; Heart and Stroke Foundation of Canada","keywords":"Versican; Cancer research; Metastasis; Cell growth; Stromal cell; Cell migration; Tumor progression; Tumor microenvironment; Mammary tumor; Biology; Signal transduction; Cell; Cell biology; Cancer; Breast cancer; Medicine; Internal medicine; Extracellular matrix; Proteoglycan","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002259314,0.000173646,0.0001801453,0.00006426009,0.0001448887,0.00008354206,0.0002436763,0.0001146351,0.00004868452],"category_scores_gemma":[0.0001705389,0.0001700712,0.00004544156,0.0001150035,0.0001069007,0.00001831064,0.0001537878,0.0002550888,0.00001082445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001208469,"about_ca_system_score_gemma":0.00009993466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002427112,"about_ca_topic_score_gemma":0.000120053,"domain_scores_codex":[0.9987543,0.00005931105,0.0001874516,0.0004142943,0.0002634488,0.0003212171],"domain_scores_gemma":[0.9992059,0.00002075083,0.00007379142,0.0003232289,0.0001936939,0.0001826748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004839978,0.0003206001,0.00268151,0.00009914943,0.00009985064,0.000002724683,0.00006696246,2.752215e-7,0.9953213,0.00001374193,0.0008946643,0.0004508622],"study_design_scores_gemma":[0.0003997259,0.0003000154,0.00009066209,0.00001698824,0.00003802288,0.000002851489,0.0000468946,0.00005979514,0.9971014,0.0000259792,0.001704447,0.000213179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980925,0.0006122001,0.0001446738,0.0004955807,0.00001801588,0.0003414315,0.0001051106,0.00002310361,0.0001674296],"genre_scores_gemma":[0.9881147,0.0002693927,0.01012351,0.000181904,0.0001342718,0.00007228021,0.0001851353,0.00003150115,0.0008873028],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009978833,"threshold_uncertainty_score":0.6935304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01259468689157601,"score_gpt":0.2113622850707409,"score_spread":0.1987675981791649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}