{"id":"W2054156770","doi":"10.1210/jcem.86.5.7472","title":"Insulin-Like Growth Factor (IGF)-Binding Protein-3 (IGFBP-3) Binds to Fibronectin (FN): Demonstration of IGF-I/IGFBP-3/FN Ternary Complexes in Human Plasma1","year":2001,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Winnipeg","funders":"","keywords":"Fibronectin; Ternary complex; Growth factor; Insulin-like growth factor-binding protein; Molecular biology; Immunoprecipitation; Binding protein; Binding site; Plasma protein binding; Heparin-binding EGF-like growth factor; Ligand binding assay; Binding domain; Chemistry; Biology; Biochemistry; Insulin-like growth factor; Receptor; Cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003663829,0.0007473077,0.0004877072,0.0006367578,0.0005753129,0.0006325675,0.0006863045,0.0006755019,0.002477362],"category_scores_gemma":[0.0004512427,0.0005115577,0.0007947758,0.0004330971,0.0003623056,0.000278968,0.0006960283,0.0007911538,0.00134586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008566374,"about_ca_system_score_gemma":0.0004375965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009857733,"about_ca_topic_score_gemma":0.007816004,"domain_scores_codex":[0.9996264,0.00005694156,0.00002782504,0.00006867285,0.0001541948,0.00006583607],"domain_scores_gemma":[0.9997564,0.00007038364,0.00003100525,0.00001546404,0.00005430119,0.00007236593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008217984,0.00002477111,0.0003345975,0.00005079135,0.000007839774,0.0001219529,0.00002874529,0.00001797576,0.9986644,0.0000366795,0.00006645569,0.0005637279],"study_design_scores_gemma":[0.00003710914,0.000320615,0.01931777,0.00002050612,0.00004990333,0.001433778,0.00008527515,0.003001654,0.9703723,0.0001341185,0.005204505,0.00002254482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9300122,0.0088804,0.05431111,0.0006511825,0.0002412228,0.0002446146,0.001262692,0.0005303192,0.003866095],"genre_scores_gemma":[0.9362864,0.00249287,0.05076912,0.0003880185,0.00009921659,0.0002115493,0.002700473,0.0001127724,0.006939539],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009857733,"threshold_uncertainty_score":0.01960075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06216065787629781,"score_gpt":0.3606417587000947,"score_spread":0.2984811008237969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}