{"id":"W2054164997","doi":"10.1006/geno.2000.6364","title":"Expression and Genetic Analysis of XIAP-Associated Factor 1 (XAF1) in Cancer Cell Lines","year":2000,"lang":"en","type":"article","venue":"Genomics","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":212,"is_retracted":false,"has_abstract":false,"ca_institutions":"Aegera Therapeutics (Canada); Ottawa Regional Cancer Foundation; University of Ottawa","funders":"National Cancer Institute; Medical Research Council; Royal Society of Canada; Howard Hughes Medical Institute","keywords":"XIAP; Biology; Inhibitor of apoptosis; Locus (genetics); Loss of heterozygosity; Gene; Molecular biology; Gene expression; Genetics; Cancer cell; Cancer research; Apoptosis; Programmed cell death; Allele; Caspase; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002752115,0.00006967919,0.0001250894,0.0000393116,0.00001915431,0.000005420099,0.00004602415,0.0001085982,0.0001464267],"category_scores_gemma":[0.00000274893,0.00006421077,0.00004887695,0.00009232775,0.00001409392,0.000001475188,0.00002217498,0.0000216362,4.960593e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001698142,"about_ca_system_score_gemma":0.00001933862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001958137,"about_ca_topic_score_gemma":0.0005237923,"domain_scores_codex":[0.9995399,0.00001875658,0.0001476871,0.0001588769,0.00004123341,0.00009353719],"domain_scores_gemma":[0.9997768,0.000003566526,0.00005531562,0.0001160624,0.00002086233,0.000027394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002018119,0.00003252812,0.00477005,0.000005482108,0.00004414136,3.29917e-7,0.00009472473,0.005254051,0.9805176,5.507203e-7,0.00001513828,0.009245232],"study_design_scores_gemma":[0.0004982772,0.00007250441,0.164685,0.000008078909,0.0001355916,4.20426e-7,0.00003723218,0.006125296,0.8254673,0.00002222208,0.002793238,0.0001548284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997142,0.002495808,0.0001225281,0.000007463844,0.000027305,0.00006581647,0.00004642028,0.000002237793,0.000090417],"genre_scores_gemma":[0.9925631,0.006256534,0.0004216635,0.0000238923,0.00003072468,0.000004222431,0.00008797176,0.00000802513,0.0006038925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.159915,"threshold_uncertainty_score":0.2618439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007798351545115824,"score_gpt":0.2294588600423536,"score_spread":0.2216605084972378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}