{"id":"W2054164997","doi":"10.1006/geno.2000.6364","title":"Expression and Genetic Analysis of XIAP-Associated Factor 1 (XAF1) in Cancer Cell Lines","year":2000,"lang":"en","type":"article","venue":"Genomics","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":212,"is_retracted":false,"has_abstract":false,"ca_institutions":"Aegera Therapeutics (Canada); Ottawa Regional Cancer Foundation; University of Ottawa","funders":"National Cancer Institute; Medical Research Council; Royal Society of Canada; Howard Hughes Medical Institute","keywords":"XIAP; Biology; Inhibitor of apoptosis; Locus (genetics); Loss of heterozygosity; Gene; Molecular biology; Gene expression; Genetics; Cancer cell; Cancer research; Apoptosis; Programmed cell death; Allele; Caspase; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002138584,0.0003638611,0.0002401524,0.0006425462,0.0003429784,0.0003351414,0.0002997358,0.0002772387,0.0008530741],"category_scores_gemma":[0.0001589001,0.0002492169,0.0003072052,0.0005045275,0.0002509269,0.0002385506,0.0001585462,0.0007371992,0.0004284308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006593311,"about_ca_system_score_gemma":0.0002622903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00219577,"about_ca_topic_score_gemma":0.002080456,"domain_scores_codex":[0.9998473,0.00002537197,0.00001633506,0.00003060712,0.00004803577,0.00003230815],"domain_scores_gemma":[0.9998185,0.00006064291,0.00003778523,0.00003376758,0.00002266157,0.00002673621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002616395,0.00001301027,0.0000784452,0.000009525308,0.000002708852,0.00001869313,0.00001076306,0.00006218672,0.9993932,0.0001189288,0.00001899341,0.0002472344],"study_design_scores_gemma":[0.00000752669,0.00005891318,0.002351408,0.000001398446,0.00001503042,0.0001304914,0.00001876761,0.0005907801,0.9956048,0.00003669827,0.001181843,0.00000244092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981737,0.001385251,0.01211613,0.0001934753,0.00003179467,0.00007917517,0.002107032,0.0002146524,0.00213553],"genre_scores_gemma":[0.9810773,0.001356597,0.008381547,0.00007324532,0.00001224482,0.00009850352,0.004211387,0.00008918958,0.004699934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00219577,"threshold_uncertainty_score":0.004783809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007798351545115824,"score_gpt":0.2294588600423536,"score_spread":0.2216605084972378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}