{"id":"W2054165177","doi":"10.1016/j.cyto.2010.07.374","title":"PS3-35 Caspase-1 processes high mobility group box 1 and is required for its release during infection and septic shock","year":2010,"lang":"en","type":"article","venue":"Cytokine","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Septic shock; Shock (circulatory); Medicine; Immunology; Internal medicine; Sepsis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000390147,0.0005568481,0.0004234669,0.0005011681,0.0004510565,0.0007578301,0.0003193064,0.0005435421,0.002590915],"category_scores_gemma":[0.0005369134,0.0003489708,0.0005077795,0.0002995735,0.0007261238,0.0009364826,0.0004497234,0.001450478,0.001114273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009413222,"about_ca_system_score_gemma":0.0004971637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005080555,"about_ca_topic_score_gemma":0.0005396391,"domain_scores_codex":[0.999537,0.00005949531,0.00003890409,0.00007658074,0.0001053746,0.0001826025],"domain_scores_gemma":[0.9995413,0.00006204995,0.0001601666,0.00006171045,0.00005762066,0.0001172035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001042595,0.00003081044,0.0004785799,0.00003101586,0.000005896257,0.00009099567,0.00003057612,0.00004980325,0.9969162,0.0001910172,0.0001026699,0.001029876],"study_design_scores_gemma":[0.00006668239,0.0003008486,0.02145771,0.000010178,0.00001625705,0.0009082493,0.000128583,0.001305879,0.9736343,0.00041514,0.001742357,0.0000138263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989953,0.002661904,0.005264356,0.0004575653,0.0001168028,0.0000343586,0.0006363362,0.0001336108,0.0007420597],"genre_scores_gemma":[0.9938332,0.0004830766,0.002161158,0.00009423655,0.00002813374,0.00003222733,0.001124662,0.00003207519,0.002211312],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002590915,"threshold_uncertainty_score":0.008667529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008980499551960813,"score_gpt":0.2332550231357403,"score_spread":0.2242745235837795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}