{"id":"W2054165177","doi":"10.1016/j.cyto.2010.07.374","title":"PS3-35 Caspase-1 processes high mobility group box 1 and is required for its release during infection and septic shock","year":2010,"lang":"en","type":"article","venue":"Cytokine","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Septic shock; Shock (circulatory); Medicine; Immunology; Internal medicine; Sepsis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000196196,0.0001393377,0.0001837365,0.00008207968,0.0002633237,0.00002336448,0.00004476866,0.0002260009,0.0001127563],"category_scores_gemma":[0.0003193282,0.00012642,0.00002971449,0.00009082918,0.000109803,0.0002588332,0.00004907922,0.0001802869,0.00002749213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001703582,"about_ca_system_score_gemma":0.00003332063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007893817,"about_ca_topic_score_gemma":0.0001051996,"domain_scores_codex":[0.9992349,0.00004790129,0.0002168425,0.0002685376,0.00002030604,0.0002115813],"domain_scores_gemma":[0.9994877,0.0001187426,0.00009125521,0.0001743753,0.0001051611,0.00002277424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006345012,0.0000585857,0.001628386,0.0003127375,0.00004306051,0.000001336126,0.0004027527,6.182917e-7,0.9941426,0.0001916768,0.000168253,0.002415472],"study_design_scores_gemma":[0.001832899,0.0002519884,0.0748895,0.00004191981,0.00005608649,0.0001134247,0.0000319924,0.00001323506,0.9131349,0.0002039624,0.009261299,0.0001687707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978555,0.0009875795,0.00008918568,0.000250472,0.0002455808,0.000430034,0.00002576139,0.00007178861,0.00004406584],"genre_scores_gemma":[0.9983787,0.0002563431,0.00008141634,0.0000545185,0.00006054196,0.00008877261,0.00009199973,0.0000145996,0.0009731309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0810077,"threshold_uncertainty_score":0.5155257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008980499551960813,"score_gpt":0.2332550231357403,"score_spread":0.2242745235837795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}