{"id":"W2054172055","doi":"10.1002/cncr.22961","title":"Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors","year":2007,"lang":"en","type":"article","venue":"Cancer","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":195,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"National Cancer Institute","keywords":"Temozolomide; Medicine; Medulloblastoma; Ependymoma; Astrocytoma; Context (archaeology); Glioma; Phases of clinical research; Primitive neuroectodermal tumor; Internal medicine; Oncology; Chemotherapy; Oligodendroglioma; Radiation therapy; Surgery; Pathology; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006823201,0.0001027457,0.0002509027,0.00008340664,0.00001656133,0.00000383674,0.00002705383,0.00002161878,0.000004300277],"category_scores_gemma":[0.000003683605,0.00007039923,0.00001767031,0.000135516,0.00002380016,0.00001943704,0.00001245142,0.00006448945,6.517508e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001791644,"about_ca_system_score_gemma":0.00003474348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008717903,"about_ca_topic_score_gemma":0.0005168189,"domain_scores_codex":[0.9992627,0.00001429802,0.0001945205,0.0001817925,0.0001450568,0.0002016647],"domain_scores_gemma":[0.9996542,0.000005667865,0.00007058422,0.0001257188,0.00002886961,0.0001149722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006855215,0.003320617,0.9767407,0.00008681749,0.00006922465,0.0001941547,0.0004547558,0.000008293893,0.0001258105,0.000004132276,0.00003155433,0.01827848],"study_design_scores_gemma":[0.01626408,0.001631483,0.9784956,0.001175179,0.0001270088,0.00005255883,0.0007105808,0.00001549626,0.00145887,1.96978e-7,0.000005119466,0.00006379557],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977109,0.001237007,0.000001809031,0.00002221924,0.00005584511,0.0009180352,0.00001087947,0.00001322651,0.00003010548],"genre_scores_gemma":[0.9998329,0.0000330775,0.0000109146,0.00001886615,0.00004933973,0.00003632859,0.000004556482,0.0000109347,0.000003100848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01821468,"threshold_uncertainty_score":0.2870797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01043103189606357,"score_gpt":0.28917638506221,"score_spread":0.2787453531661464,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}